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Results for "

Aristolochic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Aquaporin (1) Aryl Hydrocarbon Receptor (2) Cadherin (1) Caspase (1) CDK (2) DNA Alkylator/Crosslinker (2) Drug Metabolite (2) Endogenous Metabolite (2) Interleukin Related (2) Isotope-Labeled Compounds (1) NF-κB (3) Phosphodiesterase (PDE) (2) Phospholipase (2) Reference Standards (6) TGF-beta/Smad (1)
By Research Areas:	Cancer (13) Endocrinology (1) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0511

Aristolochic acid B 1 Publications Verification Aristolochic acid II	DNA Alkylator/Crosslinker	Cancer
Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .

HY-N0510A

Aristolochic acid A sodium Maximum Cited Publications 10 Publications Verification Aristolochic acid I sodium; TR 1736 sodium	NF-κB	Cancer
Aristolochic acid A (Aristolochic acid I) sodium is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A sodium significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A sodium reduces BLCAP gene expression in human cell lines .

HY-N0510

Aristolochic acid A Maximum Cited Publications 10 Publications Verification Aristolochic acid I; TR 1736	NF-κB	Cancer
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .

HY-N1465

Aristolochic acid D Aristolochic acid-IVa	Phosphodiesterase (PDE) CDK Interleukin Related	Inflammation/Immunology Cancer
Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-N1450

Aristolochic acid C	Phospholipase	Cancer
Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A₂ (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-N8500

Aristolochic acid Ia	Drug Metabolite	Others
Aristolochic acid Ia is an oxidative metabolite of aristolochic acid I, which can be used to study the detoxification pathway of aristolochic acid metabolism .

HY-N0511R

Aristolochic acid B (Standard) Aristolochic acid II (Standard)	Reference Standards DNA Alkylator/Crosslinker	Cancer
Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .

HY-N1465R

Aristolochic acid D (Standard) Aristolochic acid-IVa (Standard)	Reference Standards CDK Phosphodiesterase (PDE) Interleukin Related	Inflammation/Immunology Cancer
Aristolochic acid D (Standard) (Aristolochic acid-IVa (Standard)) is the analytical standard of Aristolochic acid D (HY-N1465). This product is intended for research and analytical applications. Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-N1450R

Aristolochic acid C (Standard)	Reference Standards Phospholipase	Cancer
Aristolochic acid C (Standard) is the analytical standard of Aristolochic acid C. This product is intended for research and analytical applications. Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-N0510R

Aristolochic acid A (Standard) Aristolochic acid I (Standard); TR 1736 (Standard)	Reference Standards NF-κB	Cancer
Aristolochic acid A (Standard) is the analytical standard of Aristolochic acid A. This product is intended for research and analytical applications. Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .

HY-N11445

Aristolochic acid Va	Others	Others
Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants .

HY-N7951

Aristolochic acid III	Others	Others
Aristolochic acid III is a natural product that can be isolated from the leaves of Aristolochia debilis .

HY-N2012

7-Hydroxyaristolochic acid A	Others	Inflammation/Immunology
7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .

HY-N11562

Aristololactam II	Others	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

HY-135772

12-Ketodeoxycholic acid 12-Ketolithocholic acid	Endogenous Metabolite	Metabolic Disease
12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury

HY-135772R

12-Ketodeoxycholic acid (Standard) 12-Ketolithocholic acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
12-Ketodeoxycholic acid (Standard) is the analytical standard of 12-Ketodeoxycholic acid. This product is intended for research and analytical applications. 12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]

HY-N2013

Aristolactam I 1 Publications Verification Aristololactam; Aristolactam	Drug Metabolite Aquaporin Cadherin TGF-beta/Smad	Endocrinology Cancer
Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .

HY-114740

β-Naphthoflavone 1 Publications Verification 5,6-Benzoflavone; beta-NF	Aryl Hydrocarbon Receptor Apoptosis	Neurological Disease Cancer
β-Naphthoflavone is an exogenous aryl hydrocarbon receptor (AHR) ligand. β-Naphthoflavone can activate AHR to participate in various biological processes, including cell growth, differentiation, apoptosis, and metabolism. β-Naphthoflavone has antioxidant activity and can exert its antioxidant function by regulating the activity of antioxidant enzymes. β-Naphthoflavone is also a non-carcinogenic CYP1A inducer and can be used to treat aristolochic acid (AAI) induced renal injury .

HY-N2013R

Aristolactam I (Standard) Aristololactam (Standard); Aristolactam (Standard)	Reference Standards Caspase Apoptosis	Inflammation/Immunology
Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .

HY-114740R

β-Naphthoflavone (Standard)	Aryl Hydrocarbon Receptor Apoptosis	Neurological Disease Cancer
β-Naphthoflavone (Standard) is the analytical standard of β-Naphthoflavone. This product is intended for research and analytical applications. β-Naphthoflavone is an exogenous aryl hydrocarbon receptor (AHR) ligand. β-Naphthoflavone can activate AHR to participate in various biological processes, including cell growth, differentiation, apoptosis, and metabolism. β-Naphthoflavone has antioxidant activity and can exert its antioxidant function by regulating the activity of antioxidant enzymes. β-Naphthoflavone is also a non-carcinogenic CYP1A inducer and can be used to treat aristolochic acid (AAI) induced renal injury .

Cat. No.	Product Name	Type

HY-N0510A

Aristolochic acid A sodium 5+ Cited Publications Aristolochic acid I sodium; TR 1736 sodium	Biochemical Assay Reagents
Aristolochic acid A (Aristolochic acid I) sodium is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A sodium significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A sodium reduces BLCAP gene expression in human cell lines .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0511

Aristolochic acid B 1 Publications Verification Aristolochic acid II	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	DNA Alkylator/Crosslinker
Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .

HY-N0510

Aristolochic acid A Maximum Cited Publications 10 Publications Verification Aristolochic acid I; TR 1736	Alkaloids Structural Classification other families Aristolochia debilis Sieb. et Zucc. Classification of Application Fields Other Alkaloids Source classification Plants Aristolochiaceae Disease Research Fields Cancer	NF-κB
Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .

HY-N1465

Aristolochic acid D Aristolochic acid-IVa	Structural Classification Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields Cancer	Phosphodiesterase (PDE) CDK Interleukin Related
Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-N1450

Aristolochic acid C	Structural Classification Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields Cancer	Phospholipase
Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A₂ (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-N11445

Aristolochic acid Va	Structural Classification Natural Products Aristolochia debilis Sieb. et Zucc. Source classification Plants Aristolochiaceae	Others
Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants .

HY-N8500

Aristolochic acid Ia	Structural Classification Natural Products Aristolochia debilis Sieb. et Zucc. Source classification Plants Aristolochiaceae	Drug Metabolite
Aristolochic acid Ia is an oxidative metabolite of aristolochic acid I, which can be used to study the detoxification pathway of aristolochic acid metabolism .

HY-N0511R

Aristolochic acid B (Standard) Aristolochic acid II (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards DNA Alkylator/Crosslinker
Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .

HY-N1465R

Aristolochic acid D (Standard) Aristolochic acid-IVa (Standard)	Structural Classification Monophenols other families Ketones, Aldehydes, Acids Source classification Phenols Plants	Reference Standards CDK Phosphodiesterase (PDE) Interleukin Related
Aristolochic acid D (Standard) (Aristolochic acid-IVa (Standard)) is the analytical standard of Aristolochic acid D (HY-N1465). This product is intended for research and analytical applications. Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-N1450R

Aristolochic acid C (Standard)	Structural Classification Monophenols other families Source classification Phenols Plants	Reference Standards Phospholipase
Aristolochic acid C (Standard) is the analytical standard of Aristolochic acid C. This product is intended for research and analytical applications. Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .

HY-N0510R

Aristolochic acid A (Standard) Aristolochic acid I (Standard); TR 1736 (Standard)	Alkaloids Structural Classification other families Aristolochia debilis Sieb. et Zucc. Other Alkaloids Source classification Plants Aristolochiaceae	Reference Standards NF-κB
Aristolochic acid A (Standard) is the analytical standard of Aristolochic acid A. This product is intended for research and analytical applications. Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines .

HY-N7951

Aristolochic acid III	Structural Classification Aristolochia debilis Sieb. et Zucc. Ketones, Aldehydes, Acids Source classification Plants Aristolochiaceae	Others
Aristolochic acid III is a natural product that can be isolated from the leaves of Aristolochia debilis .

HY-N2012

7-Hydroxyaristolochic acid A	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Aristolochia Plants Aristolochiaceae Inflammation/Immunology Disease Research Fields	Others
7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .

HY-N11562

Aristololactam II	Structural Classification Alkaloids Stephania cepharantha Hayata Pyrrole Alkaloids Source classification Plants Menispermaceae	Others
Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII .

HY-135772

12-Ketodeoxycholic acid 12-Ketolithocholic acid	Structural Classification Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury

HY-135772R

12-Ketodeoxycholic acid (Standard) 12-Ketolithocholic acid (Standard)	Structural Classification Microorganisms Source classification Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite
12-Ketodeoxycholic acid (Standard) is the analytical standard of 12-Ketodeoxycholic acid. This product is intended for research and analytical applications. 12-Ketodeoxycholic acid (12-Ketolithocholic acid) is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]

HY-N2013

Aristolactam I 1 Publications Verification Aristololactam; Aristolactam	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Drug Metabolite Aquaporin Cadherin TGF-beta/Smad
Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .

HY-N2013R

Aristolactam I (Standard) Aristololactam (Standard); Aristolactam (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards Caspase Apoptosis
Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis .

Cat. No.	Product Name	Chemical Structure

HY-176347S

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

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Aristolochic

Inhibitors & Agonists

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Isotope-Labeled Compounds

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