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Results for "

Antidiarrheal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Autophagy (2) Calcium Channel (5) CFTR (2) Chloride Channel (1) Drug Derivative (1) Isotope-Labeled Compounds (3) Neprilysin (3) Opioid Receptor (3) Reference Standards (4) SARS-CoV (1) Sodium Channel (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (1) Metabolic Disease (11) Neurological Disease (9)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-124343

Diethylhomospermine DEHSPM	Drug Derivative	Cancer
Diethylhomospermine is a polyamine analogue. Diethylhomospermine has antitumor and antidiarrheal activity .

HY-156131

Loperamide Maximum Cited Publications 8 Publications Verification ADL 2-1294	Opioid Receptor	Inflammation/Immunology
Loperamide (ADL 2-1294) is a selective μ opioid receptor agonist with K_is of 3, 48 and 1156 nM against μ, δ and κ opioid receptor, respectively. Loperamide can be used as an antidiarrheal agent .

HY-17399

Racecadotril 3 Publications Verification Acetorphan	Neprilysin	Metabolic Disease
Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with K_is of 4500 and 6.1 nM, , respectively. Antidiarrheal agent .

HY-I0637

Isovanillin 3-Hydroxy-4-methoxybenzaldehyde	Others	Neurological Disease Metabolic Disease
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-18337

IOWH-032 4 Publications Verification	CFTR SARS-CoV	Infection Metabolic Disease
IOWH-032 is a a synthetic anti-secretory molecule, is a potent CFTR inhibitor with an IC₅₀ value of 8 μM. IOWH-032 also is a anti-diarrheal agent .

HY-107358

Lidamidine WHR-1142A free base	Adrenergic Receptor	Metabolic Disease
Lidamidine (WHR-1142A free base) is an α2-adrenergic receptor agonist and antidiarrheal agent .

HY-17399R

Racecadotril (Standard) Acetorphan (Standard)	Reference Standards Neprilysin	Metabolic Disease
Racecadotril (Standard) is the analytical standard of Racecadotril. This product is intended for research and analytical applications. Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with K_is of 4500 and 6.1 nM, , respectively. Antidiarrheal agent .

HY-107358A

Lidamidine hydrochloride WHR-1142A	Adrenergic Receptor	Others
Lidamidine hydrochloride (WHR-1142A) is an α2-adrenergic receptor agonist and antidiarrheal agent .

HY-I0637S

Isovanillin-d3 3-Hydroxy-4-methoxybenzaldehyde-d₃	Isotope-Labeled Compounds	Metabolic Disease
Isovanillin-d₃ is the deuterium labeled Isovanillin . Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-I0637R

Isovanillin (Standard) 3-Hydroxy-4-methoxybenzaldehyde (Standard)	Reference Standards Others	Neurological Disease Metabolic Disease
Isovanillin (Standard) is the analytical standard of Isovanillin. This product is intended for research and analytical applications. Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-B0418A

Loperamide hydrochloride 5+ Cited Publications R-18553 hydrochloride	Opioid Receptor Autophagy	Neurological Disease Metabolic Disease Cancer
Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist . Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect .

HY-122133

CI 750	Others	Metabolic Disease
CI 750 is a potent and orally active antidiarrheal agent. CI 750 increases the motor pattern of the gastrointestinal tract. CI 750 shows a constipating activity. CI 750 shows no analgesic, addiction liability, or anticholinergic pharmacological activity .

HY-108772

Crofelemer Provir; SP 303	CFTR Chloride Channel	Others
Crofelemer (Provir) is an orally active antidiarrheal agent. Crofelemer acts on the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC) , which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer can be used in the research of diarrheal diseases .

HY-17399S

Racecadotril-d5 Acetorphan-d₅	Isotope-Labeled Compounds Neprilysin	Metabolic Disease
Racecadotril-d₅ is the deuterium labeled Racecadotril. Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with K_is of 4500 and 6.1 nM, , respectively. Antidiarrheal agent .

HY-B0418AR

Loperamide hydrochloride (Standard) R-18553 hydrochloride (Standard)	Reference Standards Opioid Receptor Autophagy	Neurological Disease Metabolic Disease Cancer
Loperamide (hydrochloride) (Standard) is the analytical standard of Loperamide (hydrochloride). This product is intended for research and analytical applications. Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist . Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect .

HY-107349

Fenoverine Spasmopriv	Calcium Channel	Neurological Disease
Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms .

HY-107349S

Fenoverine-d8 Spasmopriv-d₈	Calcium Channel Isotope-Labeled Compounds	Neurological Disease
Fenoverine-d₈ is the deuterium labeled Fenoverine. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms .

HY-107349R

Fenoverine (Standard) Spasmopriv (Standard)	Reference Standards Calcium Channel	Neurological Disease
Fenoverine (Standard) is the analytical standard of Fenoverine. This product is intended for research and analytical applications. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms .

HY-105084

Lubeluzole	Sodium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Cancer
Lubeluzole is the S-isomer of benzothiazole derivative. Lubeluzole can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole exhibits anti-ischemic and neuroprotective effects. Lubeluzole also shows anti-bacterial and anti-diarrheal potential. Lubeluzole can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .

HY-105084A

Lubeluzole dihydrochloride	Sodium Channel Calcium Channel	Infection Cardiovascular Disease Neurological Disease Cancer
Lubeluzole dihydrochloride is the dihydrochloride salt of Lubeluzole (HY-105084). Lubeluzole is the S-isomer of benzothiazole derivative. Lubeluzole can inhibit glutamate release, glutamate-activated NO synthesis and block voltage-gated Sodium Channel and Calcium Channel. Lubeluzole exhibits anti-ischemic and neuroprotective effects. Lubeluzole also shows anti-bacterial and anti-diarrheal potential. Lubeluzole can inhibit cardiac sodium channel and prolong cardiac action potential. Lubeluzole can inhibit cancer cells proliferation and invasion and shows chemosensitizing effect. Lubeluzole can be used for the researches of cancer, infection, neurological and cardiovascular disease such as stroke, infectious diarrhea and ovarian .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-I0637

Isovanillin 3-Hydroxy-4-methoxybenzaldehyde	Monophenols Ketones, Aldehydes, Acids Source classification Asclepiadaceae Phenols Plants Periploca sepium Bunge	Others
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-I0637R

Isovanillin (Standard) 3-Hydroxy-4-methoxybenzaldehyde (Standard)	Monophenols Ketones, Aldehydes, Acids Source classification Asclepiadaceae Phenols Plants Periploca sepium Bunge	Reference Standards Others
Isovanillin (Standard) is the analytical standard of Isovanillin. This product is intended for research and analytical applications. Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

Cat. No.	Product Name	Chemical Structure

HY-107349S

Fenoverine-d8
Fenoverine-d₈ is the deuterium labeled Fenoverine. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms .

Fenoverine-d8

Fenoverine-d₈ is the deuterium labeled Fenoverine. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms .

HY-I0637S

Isovanillin-d3
Isovanillin-d₃ is the deuterium labeled Isovanillin . Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-17399S

Racecadotril-d5
Racecadotril-d₅ is the deuterium labeled Racecadotril. Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with K_is of 4500 and 6.1 nM, , respectively. Antidiarrheal agent .

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