2. Search Result
Search Result
Results for "

ADP derivative

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134279
    8-Br-NAD+ sodium

    		Calcium Channel Others
    8-Br-NAD+ sodium is an NAD+ derivative that acts as a substrate for transfer to diversely modified ADP-ribosylated molecules .
    8-Br-NAD+ sodium
  • HY-173579
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate trisodium

    2'(3')-AEC-ADP trisodium

    		 Nucleoside Antimetabolite/Analog Others
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate (2'(3')-AEC-ADP) trisodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918).
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate trisodium
  • HY-131838A
    N6-4-aminobutyl-ADP trisodium

    6-AB-ADP trisodium

    		 Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Others
    N6-4-aminobutyl-ADP (6-AB-ADP) trisodium is an ADP derivative that can be used as a nucleotide mimetic or coupling agent for labeling enzyme substrates (such as kinases), constructing biological probes, or functionalizing nucleotide chains .
    N6-4-aminobutyl-ADP trisodium
  • HY-131831A
    6-Bn-ADP sodium

    N6-benzyl ADP sodium

    		 ATP Synthase Cancer
    6-Bn-ADP (N6-benzyl ADP) sodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918) that inhibits ATP hydrolysis. 6-Bn-ADP sodium inhibits the ATPase activities of Mortalin, Hsc70, and Hsp70 protein with Kis of 86.51 μM, 294.5 μM, and 1612 μM, respectively .
    6-Bn-ADP sodium
  • HY-131776A
    2-Chloro-ADP sodium

    2-Chloroadenosine 5′-diphosphate sodium

    		 Adenylate Cyclase HSP Cardiovascular Disease
    2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) sodium is a Adenosine 5'-diphosphate (ADP; HY-W010918) derivative that induces human platelet aggregation and inhibits stimulated adenylate cyclase . 2-Chloro-ADP sodium inhibits mortalin nucleotide-binding domain (NBD) with a Ki of 45.05 μM .
    2-Chloro-ADP sodium
  • HY-131776
    2-Chloro-ADP

    2-Chloroadenosine 5′-diphosphate

    		 Adenylate Cyclase HSP Cardiovascular Disease
    2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) sis a Adenosine 5'-diphosphate (ADP; HY-W010918) derivative that induces human platelet aggregation and inhibits stimulated adenylate cyclase . 2-Chloro-ADP inhibits mortalin nucleotide-binding domain (NBD) with a Ki of 45.05 μM .
    2-Chloro-ADP
  • HY-134349A
    8-PIP-NAD+ sodium

    8-Piperidino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
    8-PIP-NAD+ sodium
  • HY-134305A
    8-MA-NAD+ sodium

    8-Methylamino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives .
    8-MA-NAD+ sodium
  • HY-134382
    7-CH-dADP

    7-Deaza-2'-deoxyadenosine-5'-O-diphosphate

    		 Nucleoside Antimetabolite/Analog Others
    7-CH-dADP (7-Deaza-2'-deoxyadenosine-5'-O-diphosphate) is a dehydroxylated and deaminated derivative of the nucleotide ADP.
    7-CH-dADP
  • HY-134382A
    7-CH-dADP trisodium

    7-Deaza-2'-deoxyadenosine-5'-O-diphosphate trisodium

    		 Nucleoside Antimetabolite/Analog Others
    7-CH-dADP (7-Deaza-2'-deoxyadenosine-5'-O-diphosphate) trisodium is a dehydroxylated and deaminated derivative of the nucleotide ADP.
    7-CH-dADP trisodium
  • HY-136501
    MRS2395

    		P2Y Receptor Cardiovascular Disease
    MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6 .
    MRS2395
  • HY-N1717
    2-Acetylbenzoic acid

    		Platelet-activating Factor Receptor (PAFR) Cardiovascular Disease
    2-Acetylbenzoic acid, a Benzoic acid (HY-N0216) derivative, is a weak platelet aggregation inhibitor. 2-Acetylbenzoic acid inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation .
    2-Acetylbenzoic acid
  • HY-134300A
    8-DMA-NAD+ sodium

    8-Dimethylamino-NAD+ sodium

    		 Endogenous Metabolite Others
    8-DMA-NAD+ (sodium) (8-Dimethylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-DMA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations .
    8-DMA-NAD+ sodium
  • HY-134280
    8-Br-NHD+

    Nicotinamide 8-Br-hypoxanthine dinucleotide

    		 Drug Derivative Others
    8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .
    8-Br-NHD+
  • HY-135218
    AV-153

    		DNA/RNA Synthesis Cancer
    AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity .
    AV-153
  • HY-131799A
    3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium

    		Nucleoside Antimetabolite/Analog Others
    3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium is an amine-modified nucleotide that can be used in the synthesis of other active compounds. The coumarin-labeled derivatives of 3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium exhibit significant fluorescence changes when interacting with myosin and can mimic the function of natural ADP .
    3'-Amino-3'-deoxyadenosine-5'-O-diphosphate sodium
  • HY-137749A
    MANT-dADP trisodium

    2'-Deoxy-3'-MANT-ADP trisodium

    		 Biochemical Assay Reagents Others
    MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y12 receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils .
    MANT-dADP trisodium
  • HY-135218A
    AV-153 free base
    1 Publications Verification

    		 DNA/RNA Synthesis Cancer
    AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity .
    AV-153 free base
  • HY-78263
    MNS
    3 Publications Verification

    NSC 170724; 5-(2-Nitrovinyl)benzodioxole

    		 Src Syk NOD-like Receptor (NLR) Integrin Cancer
    MNS (NSC 170724), the beta-nitrostyrene derivative, is an orally active tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 μM, respectively. MNS inhibits NLRP3 inflammasome and β1 integrin. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 μM, respectively. MNS is cytotoxic to a variety of cells .
    MNS

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: