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Results for "

8-13

" in MedChemExpress (MCE) Product Catalog:

49

Inhibitors & Agonists

26

Fluorescent Dye

7

Peptides

2

Isotope-Labeled Compounds

1

Antibodies

3

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2544
    [Lys8, Lys9]-Neurotensin (8-13)

    JMV438

    		 Neurotensin Receptor Neurological Disease
    [Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively .
    [Lys8, Lys9]-Neurotensin (8-13)
  • HY-P0251
    Neurotensin(8-13)
    1 Publications Verification

    		 Neurotensin Receptor Neurological Disease
    Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
    Neurotensin(8-13)
  • HY-W248594
    IR 813 tosylate

    		Fluorescent Dye Others
    IR 813 tosylate is a near-infrared (NIR) fluorescent dye and can be used for visualizing regional lymph nodes in mice .
    IR 813 tosylate
  • HY-143319
    SPH5030

    		EGFR Cancer
    SPH5030 is a selective and irreversible HER2 inhibitor. SPH5030 inhibits HER2 WT and EGFR WT with IC50s of 3.51 and 8.13 nM, respectively. SPH5030 shows excellent activities against HER2 mutants. SPH5030 can be used for the research of cancer .
    SPH5030
  • HY-P4223
    Acetyl neurotensin (8-13)

    		Neurotensin Receptor Neurological Disease
    Acetyl neurotensin (8-13) is the shortest analog of neurotensin with full binding and pharmacological activities .
    Acetyl neurotensin (8-13)
  • HY-P0251A
    Neurotensin(8-13) TFA

    		Neurotensin Receptor Neurological Disease
    Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.
    Neurotensin(8-13) TFA
  • HY-D1535
    IR 813 perchlorate

    		Fluorescent Dye Others
    IR 813 perchlorate is a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm) and can be used for visualizing regional lymph nodes in mice .
    IR 813 perchlorate
  • HY-135414A
    Cyanine5 NHS ester bromide

    		Fluorescent Dye Others
    Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
    Cyanine5 NHS ester bromide
  • HY-139300
    Epitinib

    HMPL-813

    		 EGFR Cancer
    Epitinib is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib can be used for the research of cancer . Epitinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Epitinib
  • HY-141496
    A-77636

    		Dopamine Receptor Neurological Disease
    A-77636 is an orally active, potent, selective and long-acting dopamine D1 receptor agonist (pEC50 = 8.13; EC50 = 1.1 nM). A-77636 shows the highest affinity (pKi = 7.40 ± 0.09; Ki = 39.8 nM) for the dopamine D1 receptor. A-77636 shows antiparkinsonian activity .
    A-77636
  • HY-149941
    hNTS1R agonist-1

    		Neurotensin Receptor Neurological Disease
    hNTS1R agonist-1 (Compound 10) is a BBB permeable hNTS1R full agonist (Ki: 6.9 nM) . hNTS1R agonist-1 increases motor function and memory in a mouse model of Parkinson's disease (PD). hNTS1R agonist-1 is a Neurotensin(8-13) analog and is a neuroprotective agent .
    hNTS1R agonist-1
  • HY-129707
    AMG 837 hemicalcium

    		Free Fatty Acid Receptor Metabolic Disease
    AMG 837 hemicalcium is a potent, orally bioavailable and partial agonist of GPR40/FFA1. AMG 837 hemicalcium inhibits specific [ 3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8.13. AMG 837 hemicalcium could enhance insulin secretion and lower glucose levels in rodents .
    AMG 837 hemicalcium
  • HY-100935S
    Cimaterol-d7

    CL 263780-d7

    		 Isotope-Labeled Compounds Adrenergic Receptor Endocrinology
    Cimaterol-d7 is the deuterium labeled Cimaterol. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50s=8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively). Cimaterol has been used in farmed animals to increase carcass mass and to alter muscle and fat deposition.
    Cimaterol-d7
  • HY-139300A
    Epitinib succinate

    HMPL-813 succinate

    		 EGFR Cancer
    Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer . Epitinib (succinate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Epitinib succinate
  • HY-168606A
    p53-MDM2-IN-7 hydrochloride

    		MDM-2/p53 Cancer
    p53-MDM2-IN-7 (compound 6d) (hydrochloride) is a p53-MDM2 inhibitor. p53-MDM2-IN-7 has an IC50 value of 8.13 μM against A549 cells. p53-MDM2-IN-7 can be used in anti-cancer research .
    p53-MDM2-IN-7 hydrochloride
  • HY-13967B
    AMG 837 calcium hydrate
    2 Publications Verification

    		 Free Fatty Acid Receptor Metabolic Disease
    AMG 837 calcium hydrate is a potent, orally bioavailable and partial agonist of GPR40/FFA1. AMG 837 calcium hydrate inhibits specific [ 3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8.13. AMG 837 calcium hydrate could enhance insulin secretion and lower glucose levels in rodents . AMG 837 (calcium hydrate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    AMG 837 calcium hydrate
  • HY-P5846
    Muscarinic toxin 3

    MT3

    		 mAChR Adrenergic Receptor Neurological Disease
    Muscarinic toxin 3 (MT3) is a potent and non-competitive mAChR and adrenoceptors antagonist with pIC50s of 6.71, 8.79, 8.86, 7.57, 8.13, 8.49, <6.5, 7.29 against M1, M4, α1A, α1B, α1D,α2A,α2B and α2C receptors, respectively. Muscarinic toxin 3 displays prominent adrenoceptor activity .
    Muscarinic toxin 3
  • HY-177103
    Midobrutinib

    		Btk Cancer
    Midobrutinib (Example 13) is a BTK inhibitor (IC50: 0.813 nM). Midobrutinib can be used for research of diseases involving BTK, particularly cancer .
    Midobrutinib
  • HY-D1744
    ICG Maleimide

    		Fluorescent Dye Others
    ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
    ICG Maleimide
  • HY-133124
    PARP/PI3K-IN-1

    		PARP PI3K Apoptosis Cancer
    PARP/PI3K-IN-1 (compound 15) is a potent PARP/PI3K inhibitor with pIC50 values of 8.22, 8.44, 8.25, 6.54, 8.13, 6.08 for PARP-1, PARP-2, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively. PARP/PI3K-IN-1 is a highly effective anticancer compound targeted against a wide range of oncologic diseases .
    PARP/PI3K-IN-1
  • HY-W588722
    ICG-DBCO

    		Fluorescent Dye Others
    ICG-DBCO is a near-infrared fluorescent dye that is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling.Ex/Em = 789/813 nm
    ICG-DBCO
  • HY-P1256C
    JMV 449 acetate

    		Neurotensin Receptor Neurological Disease
    JMV 449 acetate is a potent neurotensin receptor agonist. JMV 449 acetate shows an IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 acetate has highly potent and long-lasting hypothermic and analgesic effects in the mouse .
    JMV 449 acetate
  • HY-P1256
    JMV 449

    		Neurotensin Receptor Neurological Disease
    JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [ 125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse .
    JMV 449
  • HY-D0711
    Indocyanine green
    Maximum Cited Publications
    28 Publications Verification

    Foxgreen; IC Green; Cardiogreen

    		 Fluorescent Dye Cancer
    Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) .
    Indocyanine green
  • HY-D2617
    ICG PEG DBCO (MW 5000)

    		Fluorescent Dye Others
    ICG PEG DBCO (MW 5000) is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG DBCO (MW 5000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em = 785/813 nm).
    ICG PEG DBCO (MW 5000)
  • HY-D2619
    ICG PEG FA (MW 5000)

    		Fluorescent Dye Others
    ICG PEG FA (MW 5000) is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG FA (MW 5000) is widely used in drug delivery and biomaterial labeling (Ex/Em = 785/813 nm).
    ICG PEG FA (MW 5000)
  • HY-D2618
    ICG PEG FA (MW 2000)

    		Fluorescent Dye Others
    ICG PEG FA (MW 2000) is a fluorescently labeled biomolecule containing Indocyanine green (ICG) (HY-D0711) fluorescent dye, polyethylene glycol (PEG) and Folic acid (FA) (HY-16637). ICG PEG FA (MW 2000) is widely used in drug delivery and biomaterial labeling (Ex/Em = 785/813 nm).
    ICG PEG FA (MW 2000)
  • HY-D2616
    ICG PEG DBCO (MW 2000)

    		Fluorescent Dye Others
    ICG PEG DBCO (MW 2000) is a fluorescent probe containing Indocyanine green (ICG) (HY-D0711) dye. ICG PEG DBCO (MW 2000) contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups (Ex/Em = 785/813 nm).
    ICG PEG DBCO (MW 2000)
  • HY-D2614
    ICG PEG biotin (MW 2000)

    		Fluorescent Dye Others
    ICG PEG biotin (MW 2000) is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em = 785/813 nm).
    ICG PEG biotin (MW 2000)
  • HY-D2615
    ICG PEG biotin (MW 5000)

    		Fluorescent Dye Others
    ICG PEG biotin (MW 5000) is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em = 785/813 nm).
    ICG PEG biotin (MW 5000)
  • HY-15542A
    FRAX597
    5+ Cited Publications

    		 PAK Cancer
    FRAX597 is a potent group I p21-activated Kinases (PAKs) inhibitor with IC50 of 8, 13 and 19 nM for PAK1, 2 and 3.
    FRAX597
  • HY-B0284S2
    Nifedipine-13C8

    BAY-a-1040-13C8

    		 Isotope-Labeled Compounds Calcium Channel Autophagy Cardiovascular Disease
    Nifedipine-13C8 is a deuterated labeled Nifedipine . Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
    Nifedipine-13C8
  • HY-D2609
    ICG PEG DSPE (MW 1000)

    		Fluorescent Dye Others
    ICG PEG DSPE (MW 1000) is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG DSPE (MW 1000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 785/813 nm).
    ICG PEG DSPE (MW 1000)
  • HY-D2611
    ICG PEG DSPE (MW 3400)

    		Fluorescent Dye Others
    ICG PEG DSPE (MW 3400) is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG DSPE (MW 340) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 785/813 nm).
    ICG PEG DSPE (MW 3400)
  • HY-D2613
    ICG PEG DSPE (MW 10000)

    		Fluorescent Dye Others
    ICG PEG DSPE (MW 10000) is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG DSPE (MW 10000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 785/813 nm).
    ICG PEG DSPE (MW 10000)
  • HY-D2612
    ICG PEG DSPE (MW 5000)

    		Fluorescent Dye Others
    ICG PEG DSPE (MW 5000) is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 785/813 nm).
    ICG PEG DSPE (MW 5000)
  • HY-D2610
    ICG PEG DSPE (MW 2000)

    		Fluorescent Dye Others
    ICG PEG DSPE (MW 2000) is a PEG phospholipid with Indocyanine green (ICG) (HY-D0711) dye used in protein/nucelic acid labeling and fluorescence microscopy. ICG PEG DSPE (MW 2000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine (Ex/Em = 785/813 nm).
    ICG PEG DSPE (MW 2000)
  • HY-D2602
    ICG PEG NH2 (MW 5000)

    		Fluorescent Dye Others
    ICG PEG NH2 (MW 5000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 5000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
    ICG PEG NH2 (MW 5000)
  • HY-D2601
    ICG PEG NH2 (MW 3400)

    		Fluorescent Dye Others
    ICG PEG NH2 (MW 3400) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 3400) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
    ICG PEG NH2 (MW 3400)
  • HY-D2600
    ICG PEG NH2 (MW 2000)

    		Fluorescent Dye Others
    ICG PEG NH2 (MW 2000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 2000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
    ICG PEG NH2 (MW 2000)
  • HY-D2599
    ICG PEG NH2 (MW 1000)

    		Fluorescent Dye Others
    ICG PEG NH2 (MW 1000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 1000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
    ICG PEG NH2 (MW 1000)
  • HY-D2603
    ICG PEG NH2 (MW 10000)

    		Fluorescent Dye Others
    ICG PEG NH2 (MW 10000) is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG NH2 (MW 10000) can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em = 785/813 nm).
    ICG PEG NH2 (MW 10000)
  • HY-D2608
    ICG PEG N3 (MW 10000)

    		Fluorescent Dye Others
    ICG PEG N3 (MW 10000) is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG N3 (MW 10000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 785/813 nm).
    ICG PEG N3 (MW 10000)
  • HY-D2604
    ICG PEG N3 (MW 1000)

    		Fluorescent Dye Others
    ICG PEG N3 (MW 1000) is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG N3 (MW 1000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 785/813 nm).
    ICG PEG N3 (MW 1000)
  • HY-D2606
    ICG PEG N3 (MW 3400)

    		Fluorescent Dye Others
    ICG PEG N3 (MW 3400) is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG N3 (MW 3400) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 785/813 nm).
    ICG PEG N3 (MW 3400)
  • HY-D2605
    ICG PEG N3 (MW 2000)

    		Fluorescent Dye Others
    ICG PEG N3 (MW 2000) is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG N3 (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 785/813 nm).
    ICG PEG N3 (MW 2000)
  • HY-D2607
    ICG PEG N3 (MW 5000)

    		Fluorescent Dye Others
    ICG PEG N3 (MW 5000) is a Indocyanine green (ICG) (HY-D0711)-azide fluorescent dye used to label for protein and nucleic acid. ICG PEG N3 (MW 5000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 785/813 nm).
    ICG PEG N3 (MW 5000)
  • HY-W336094
    1,3-Glyceryl dilinoleate

    1,3-Dilinolein

    		 Biochemical Assay Reagents Metabolic Disease
    1,3-Glyceryl dilinoleate (Compound 8, 1,3-Dilinolein) is an unsaturated diacylglycerol with Linoleic acid (HY-N0729) (18:2) side-chains attached at both the C-1 and C-3 positions, which can be used for lipid research .
    1,3-Glyceryl dilinoleate
  • HY-101307
    BNTX maleate

    7-Benzylidenenaltrexone maleate

    		 Opioid Receptor Neurological Disease
    BNTX (7-Benzylidenenaltrexone) maleate is a δ1-opioid receptor antagonist with the Kis of 0.1, 10.8, 13.3, and 58.6 nM for δ1, δ2-, μ-, and κ-opioid receptor, respectively. BNTX maleate shows antinociceptive activity .
    BNTX maleate

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