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Results for "

5β-Cholanic acid

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Biochemical Assay Reagents

7

Natural
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2

Isotope-Labeled Compounds

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W127512
    5β-Cholanic acid
    1 Publications Verification

    		 Drug Intermediate Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid
  • HY-W018512
    7-Ketolithocholic acid
    4 Publications Verification

    3α-Hydroxy-7-oxo-5β-Cholanic acid

    		 Endogenous Metabolite Metabolic Disease
    7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
    7-Ketolithocholic acid
  • HY-W018512R
    7-Ketolithocholic acid (Standard)

    3α-Hydroxy-7-oxo-5β-Cholanic acid (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
    7-Ketolithocholic acid (Standard)
  • HY-B0172
    Lithocholic acid
    Maximum Cited Publications
    16 Publications Verification

    3α-Hydroxy-5β-Cholanic acid

    		 Autophagy Endogenous Metabolite Apoptosis FXR Metabolic Disease Cancer
    Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist .
    Lithocholic acid
  • HY-B0172R
    Lithocholic acid (Standard)
    Maximum Cited Publications
    16 Publications Verification

    3α-Hydroxy-5β-Cholanic acid (Standard)

    		 Reference Standards Autophagy Endogenous Metabolite Apoptosis FXR Metabolic Disease Cancer
    Lithocholic acid (Standard) is the analytical standard of Lithocholic acid. This product is intended for research and analytical applications. Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist .
    Lithocholic acid (Standard)
  • HY-B0172B
    Isolithocholic acid

    3β-Hydroxy-5β-Cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid

    		 Endogenous Metabolite Endocrinology
    Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
    Isolithocholic acid
  • HY-W127512R
    5β-Cholanic acid (Standard)

    		Drug Intermediate Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid (Standard)
  • HY-W127586
    5β-Cholanic acid 3,7-dione methyl ester

    		Biochemical Assay Reagents Others
    5β-Cholanic acid 3,7-dione methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    5β-Cholanic acid 3,7-dione methyl ester
  • HY-177795
    5β-Cholanic acid-3,6-dione

    3,6-Diketo-LCA

    		 Drug Derivative Others
    5β-Cholanic acid-3,6-dione is a similar substance to Lithocholic acid (LCA) (HY-B0172). 5β-Cholanic acid-3,6-dione cannot activate the Vitamin D receptor (VDR), and can be used as a negative control for studying the relationship between LCA derivatives and VDR .
    5β-Cholanic acid-3,6-dione
  • HY-W747313
    Dehydrochenodeoxycholic acid

    5β-Cholanic acid-3,7-dione; 3,7-Dioxo-5β-cholanoic acid; 3,7-Diketochenodeoxycholic acid

    		 Endogenous Metabolite Metabolic Disease
    Dehydrochenodeoxycholic acid is a ketone bile acid .
    Dehydrochenodeoxycholic acid
  • HY-W587978
    12β-Hydroxyisocholic acid

    Lagocholic acid; 3α,7α,12β-Trihydroxy-5β-Cholanic acid

    		 Endogenous Metabolite Drug Isomer Metabolic Disease
    12β-Hydroxyisocholic acid (Lagocholic acid) is a bile acid isomer that can be used in the study of bile acid metabolism .
    12β-Hydroxyisocholic acid
  • HY-129123R
    ML318 (Standard)

    		Reference Standards Antibiotic Infection
    7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
    ML318 (Standard)
  • HY-B0172S
    Lithocholic acid-d4
    1 Publications Verification

    3α-Hydroxy-5β-Cholanic acid-d4

    		 Isotope-Labeled Compounds Autophagy Apoptosis Metabolic Disease
    Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid .
    Lithocholic acid-d4
  • HY-B0172S1
    Lithocholic acid-d5

    3α-Hydroxy-5β-Cholanic acid-d5

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite Apoptosis Metabolic Disease
    Lithocholic acid-d5 is deuterium labeled Lithocholic acid.
    Lithocholic acid-d5
  • HY-B0172BR
    Isolithocholic acid (Standard)

    3β-Hydroxy-5β-Cholanic acid (Standard); 3-Epilithocholic acid (Standard); β-Lithocholic acid (Standard)

    		 Reference Standards Endogenous Metabolite Endocrinology
    Isolithocholic acid (Standard) is the analytical standard of Isolithocholic acid. This product is intended for research and analytical applications. Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].
    Isolithocholic acid (Standard)

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