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12-Deoxyphorbol 13-isobutyrate

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N16121
    12-Deoxyphorbol 13-isobutyrate

    		PKC Neurological Disease
    12-Deoxyphorbol 13-isobutyrate (ER272) (DPB), a diterpene, is a PKCα activator. 12-Deoxyphorbol 13-isobutyrate can be isolated from Euphorbia resinifera's latex. 12-Deoxyphorbol 13-isobutyrate facilitates neural stem cells (NSCs) proliferation and activation as well as TGFα release in a reaction dependent on PKCα activation. 12-Deoxyphorbol 13-isobutyrate increases cognitive performance and hippocampal neurogenesis in senescence-accelerated mouse-prone (SAMP8) models. 12-Deoxyphorbol 13-isobutyrate can be used for neurodegenerative diseases research .
    12-Deoxyphorbol 13-isobutyrate

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