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Results for "

SNAP-tag

" in MedChemExpress (MCE) Product Catalog:

44

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35

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6

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D2925
    dTCOBG

    dTCO-SNAP

    		 Biochemical Assay Reagents Others
    dTCOBG is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling .
    dTCOBG
  • HY-D2949
    SNAP-549

    		Fluorescent Dye Others
    SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
    SNAP-549
  • HY-D2941
    BGAF

    SNAP-AF

    		 Fluorescent Dye Others
    BGAF is a fluorescent diacetyl fluorescein-labeled SNAP tag fluorescent probe, specifically designed for the covalent labeling of SNAP-tag fusion proteins in living cells. BGAF utilizes the specific reaction of the human DNA repair protein hAGT to achieve specific fluorescent labeling of the target protein in the living cell environment .
    BGAF
  • HY-N15911
    18:1 PE-Benzylguanine ammonium

    		Biochemical Assay Reagents Others
    18:1 PE-Benzylguanine ammonium is a SNAP-tag reacting lipid.
    18:1 PE-Benzylguanine ammonium
  • HY-N15801
    18:1 Glutaryl PE-alendronate trisodium

    		Biochemical Assay Reagents Others
    18:1 Glutaryl PE-alendronate trisodium is a SNAP-tag reacting lipid.
    18:1 Glutaryl PE-alendronate trisodium
  • HY-D2934
    SNAP-Block

    		Biochemical Assay Reagents Others
    SNAP-Block is a membrane-permeable SNAP blocker. SNAP-Block blocks SNAP-tag .
    SNAP-Block
  • HY-D2948
    SNAP-430

    		Fluorescent Dye Others
    SNAP-430 is a (diethylamino) coumarin-labeled SNAP tag fluorescent probe. SNAP-430 can be used for making SNAP-tag fusion proteins inside living cells, on cell surfaces, or in vitro.
    SNAP-430
  • HY-N15896
    18:1 PE-PEG2000-Benzylguanine ammonium

    		Biochemical Assay Reagents Others
    18:1 PE-PEG2000-Benzylguanine ammonium is a SNAP-tag reacting lipid.
    18:1 PE-PEG2000-Benzylguanine ammonium
  • HY-D2964
    NBzF-BG

    		Fluorescent Dye Others
    NBzF-BG is a novel H2O2-specific fluorescent probe. NBzF-BG shows visible absorption centered at 505 nm and weak fluorescence with an emission maximum at 525 nm. NBzF-BG is covalently and selectively conjugated with the SNAP-tag protein, leading to formation of the fluorophore-protein conjugate (SNAP-NBzF). SNAP-NBzF rapidly reacts with H2O2 and thereby shows an enhancement in fluorescence .
    NBzF-BG
  • HY-D2966
    TMR-NO-BG

    		Fluorescent Dye Others
    TMR-NO-BG is a hybrid probe (Ex/Em: 557 nm/571 nm). TMR-NO-BG covalently connects the tetramethylrhodamine (TMR) lactone NO sensing unit with the SNAP-tag reactive benzyl guanine (BG) for achieving subcellular-specific nitric oxide (NO) detection .
    TMR-NO-BG
  • HY-D2995
    CoDi3

    		Biochemical Assay Reagents Others
    CoDi3 is a covalent dimerization inducer. CoDi3 can specifically, covalently and irreversibly induce the dimerization of two proteins that have been fused with O6-alkylguanine-DNA alkyltransferase (AGT, also known as SNAP-tag) in living cells. CoDi3 can act as a "sensor" for protein-protein interactions .
    CoDi3
  • HY-D2939
    BGSBD

    		Fluorescent Dye Others
    BGSBD is a SNAP-tag-based fluorescent probe (Ex/Em: 435 nm/516 nm) based on the environmentally sensitive fluorescent group SBD, specifically designed for protein labeling of live cells without washing. BGSBD achieves a 280-fold fluorescence enhancement after labeling by ingeniously utilizing the hydrophobic binding pocket of the SNAP-tag protein, providing an ideal tool for real-time monitoring of protein dynamics within cells .
    BGSBD
  • HY-D2930
    BG-SS-SulfoCy5

    SNAP-SS-SulfoCy5

    		 Fluorescent Dye Others
    BG-SS-SulfoCy5 is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond (Ex/Em: 649 nm/666 nm). BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .
    BG-SS-SulfoCy5
  • HY-D2935
    CoDi2

    		Biochemical Assay Reagents Others
    CoDi3 is a covalent dimerization inducer. CoDi3 can specifically, covalently and irreversibly induce the dimerization of two proteins that have been fused with O6-alkylguanine-DNA alkyltransferase (AGT, also known as SNAP-tag) in living cells. CoDi3 can act as a "sensor" for protein-protein interactions .
    CoDi2
  • HY-136936
    PYBG-BODIPY

    		Fluorescent Dye Others
    PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
    PYBG-BODIPY
  • HY-139163
    BGSN3

    		Biochemical Assay Reagents Others
    BGSN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGSN3 are reasonable (IC50=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    BGSN3
  • HY-139162
    BGN3

    		Biochemical Assay Reagents Others
    BGN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    BGN3
  • HY-D2926
    BG-Tetrazine

    BG-Tz; SNAP-Tetrazine

    		 Biochemical Assay Reagents Others
    BG-Tetrazine is a SNAP tag substrate that contains a methyl tetrazine group. BG-Tetrazine can specifically covalently label the target protein of the intracellular SNAP-tag fusion. The tetrazine group it carries can rapidly and efficiently undergo a bioorthogonal reaction with functional groups such as trans cyclooctene (TCO), thereby enabling multiple labeling, functionalization or enrichment of proteins. BG-Tetrazine can be applied in click chemistry .
    BG-Tetrazine
  • HY-151645
    Alkyne-SNAP

    		ADC Linker Others
    Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
    Alkyne-SNAP
  • HY-151646
    Alkyne-PEG5-SNAP

    Alkyne-PEG5-BG

    		 ADC Linker Others
    Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-PEG5-SNAP
  • HY-148958
    SNAP-Biotin

    		Biochemical Assay Reagents Others
    SNAP-Biotin is a biotin-labeled SNAP tag probe. SNAP-Biotin can be used for protein biotinylation .
    SNAP-Biotin
  • HY-136937
    PYBG-TMR

    		Fluorescent Dye Others
    PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    PYBG-TMR
  • HY-D2989
    BG-NH2-Ac-N3

    SNAP-NH2-Ac-N3

    		 Biochemical Assay Reagents Others
    BG-NH2-Ac-N3 is a nitrogen-containing SNAP tag with a nitro group. BG-NH2-Ac-N3 can be used for click chemistry labeling .
    BG-NH2-Ac-N3
  • HY-D2943
    BG-SS-SulfoCy3

    SNAP-SS-SulfoCy3

    		 Fluorescent Dye Others
    BG-SS-SulfoCy3 is a SulfoCy3-labeled SNAP tag fluorescent probe, which is linked by a disulfide bond to achieve selective labeling and controllable cleavage. BG-SS-SulfoCy3 can be used to study the endocytosis and trafficking of membrane proteins such as GPCRs .
    BG-SS-SulfoCy3
  • HY-131028
    Janelia Fluor® 646 TFA

    JF646 TFA

    		 Fluorescent Dye Others
    Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 646 TFA
  • HY-D2940
    SiR-SNAP

    SiR650-BG

    		 Fluorescent Dye Others
    SiR-SNAP is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .
    SiR-SNAP
  • HY-D2944
    SNAP-649

    		Fluorescent Dye Others
    SNAP-649 is a DY-649P1-labeled SNAP tag fluorescent probe.
    SNAP-649
  • HY-D2942
    BDP-V BG-BODIPY

    		Fluorescent Dye Others
    BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .
    BDP-V BG-BODIPY
  • HY-W017776
    BG-NH2

    SNAP-NH2

    		 Drug Intermediate Others
    BG-NH2 is a pharmaceutical intermediate. BG-NH2 is suitable for synthesizing fluorescent SNAP tag substrates to label RNA .
    BG-NH2
  • HY-D2981
    CoDi1

    		Biochemical Assay Reagents Others
    CoDi1 is an effective chemical crosslinking agent. CoDi1 can achieve covalent and irreversible dimerization of AGT/SNAP tag fusion proteins in living cells .
    CoDi1
  • HY-D2931
    SNAP-FAM

    		Fluorescent Dye Others
    SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe (Ex/Em: 494 nm/526 nm), specifically designed for live-cell protein labeling and real-time imaging applications .
    SNAP-FAM
  • HY-D2933
    SNAP-505

    		Fluorescent Dye Others
    SNAP-505 is a green fluorescent O6 benzylguanine derivative. SNAP-505 labels SNAP-tagged proteins covalently. SNAP-505 can be used to label cells (green) .
    SNAP-505
  • HY-131015
    HaXS8

    		Biochemical Assay Reagents Others
    HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .
    HaXS8
  • HY-D2965
    SNAP-Peroxy-Green-1

    SPG1

    		 Fluorescent Dye Others
    SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
    SNAP-Peroxy-Green-1
  • HY-D2957
    BG-Nor

    NorBG; SNAP-Nor

    		 Drug Derivative Nucleoside Antimetabolite/Analog Others
    BG-Nor (NorBG) is a Benzylguanine analogue containing Norbornene (HY-W013021). BG-Nor can be converted by cell surface SNAP tags. NorBG can be used for tetrazine-linked labeling of cells via the iEDDA reaction .
    BG-Nor
  • HY-D2952
    BOCA-1-BG

    		Fluorescent Dye Others
    BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca 2+ concentration and serves as a highly sensitive Ca 2+ fluorescent indicator .
    BOCA-1-BG
  • HY-D2924
    CBG-549-QSY7

    		Fluorescent Dye Others
    CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation .
    CBG-549-QSY7
  • HY-D2951
    BG-Kaede chromophore

    		Fluorescent Dye Others
    BG-Kaede chromophore (Compound 4c) is a SNAP-tag-specific fluorescent probe, which is designed and synthesized using the chromophore of the red fluorescent protein Kaede as a template. BG-Kaede chromophore can be used as a tool for visualizing proteins in living cells .
    BG-Kaede chromophore
  • HY-133535
    PA Janelia Fluor® 646, SE

    PA-JF646-NHS

    		 Fluorescent Dye Others
    PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ® and SNAP-tag ®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λExcitation/emission~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    PA Janelia Fluor® 646, SE
  • HY-D2958
    ZP1BG

    		Fluorescent Dye Others
    ZP1BG is a SNAP tag fluorescent probe for detecting Zn 2+, which is formed by the covalent connection of the zinc sensor ZP1 from the Zinpyr family with the benzyl guanine group. ZP1BG can be used to detect the concentration of Zn 2+ in neuronal organelles such as the Golgi apparatus and mitochondria .
    ZP1BG
  • HY-D2984
    BG-PEG-NH2

    SNAP-PEG-NH2

    		 Fluorescent Dye Others
    BG-PEG-NH2 is an amine terminated phenylguanine derivative with a polyethylene glycol (PEG) chain. BG-PEG-NH2 is an important building block for synthesizing SNAP tag labeled probes. BG-PEG-NH2 is suitable for coupling reactions in aqueous or buffer solutions, coupling of markers, and labeling of intracellular or cell surface proteins .
    BG-PEG-NH2
  • HY-175417
    VHL-SNAP2-5C

    		PROTACs Cancer
    VHL-SNAP2-5C is a SNAP-fusion protein PROTAC degrader basing on a self-labeling protein SNAP tag. VHL-SNAP2-5C by endogenous tagging enables the visualization and the selective depletion of a SNAP-fusion protein, such as CLCa andEGFP . Pink: SNAP-fusion protein ligand (HY-W128709); Blue: VHL ligase ligand (HY-112078); Black: linker (HY-Y1139)
    VHL-SNAP2-5C
  • HY-D2994
    SPY555-BG

    SNAP-MaP555

    		 Fluorescent Dye Others
    SPY555-BG is the benzylguanine derivative of SPY555 fluorophore. SPY555-BG emits light in the orange part of the UV-ViS spectrum. SPY555-BG is fluorogenic, highly cell permeable and well suited for STED and SIM superresolution imaging. SPY555-BG can be imaged with a standard Cy3 filterset. SPY555-BG can be used for widefield, confocal, SIM or STED imaging in living or fixed cells and tissue .
    SPY555-BG
  • HY-D2956
    BC-GLA-NHS

    CLIP-GLA-NHS

    		 Biochemical Assay Reagents Others
    BC-GLA-NHS is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .
    BC-GLA-NHS

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