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Results for "

MPD

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Recombinant Proteins

1

Isotope-Labeled Compounds

2

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0903
    Hexylene glycol

    2-Methyl-2,4-pentanediol; MPD

    		 Biochemical Assay Reagents Bacterial Infection
    Hexylene glycol is a low molecular weight surfactant with antimicrobial properties. Hexylene glycol is widely used in industrial chemicals and cosmetics .
    Hexylene glycol
  • HY-B0903R
    Hexylene glycol (Standard)

    2-Methyl-2,4-pentanediol (Standard); MPD (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    Hexylene glycol (Standard) is the analytical standard of Hexylene glycol. This product is intended for research and analytical applications. Hexylene glycol is a low molecular weight surfactant that is widely used as an industrial coating solvent without causing adverse health or environmental effects.
    Hexylene glycol (Standard)
  • HY-162464
    MPD2

    		PROTACs SARS-CoV Infection
    MPD2 is a Cereblon-binding ligand-based PROTAC that degrades MPro, the main protease of SARS-CoV-2. MPD2 effectively reduced MPro protein levels in 293T cells in a time-dependent manner (DC50=296 nM). MPD2 exhibited potent antiviral activity against multiple SARS-CoV-2 strains and had enhanced potency against Nirmatrelvir (HY-138687) resistant strains. MPD2 provides a new direction for antiviral drug development against SARS-CoV-2 and other emerging coronavirus pathogens (Sturcture Note:(Blue: Cereblon ligand (HY-14658), Black: linker (HY-W275882)；Red: SARS-CoV-2 MPro Inhibitor MP18 (HY-158763)) .
    MPD2
  • HY-B0903S
    Hexylene glycol-d12

    2-Methyl-2,4-pentanediol-d12; MPD-d12

    		 Isotope-Labeled Compounds Others
    Hexylene glycol-d12 is the deuterium labeled Hexylene glycol .
    Hexylene glycol-d12
  • HY-RS18453
    Mvd Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Mvd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mvd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Mvd Mouse Pre-designed siRNA Set A
    Mvd Mouse Pre-designed siRNA Set A
  • HY-RS08856
    MVD Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    MVD Human Pre-designed siRNA Set A contains three designed siRNAs for MVD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MVD Human Pre-designed siRNA Set A
    MVD Human Pre-designed siRNA Set A
  • HY-178097
    HPK1-IN-62

    		MAP4K Cancer
    HPK1-IN-62 is a selective and orally active HPK-1 inhibitor with an IC50 of 1.22 nM. HPK1-IN-62 significantly improves GLK selectivity (> 665-fold) and LCK selectivity (> 1095-fold). HPK1-IN-62 enhances T-cell activation and demonstrated synergistic effects when combined with anti-mPD-1 therapy in the MC38 tumor model, inhibiting a tumor growth. HPK1-IN-62 can be used in the researchs of colon cancer and cancer immunotherapy .
    HPK1-IN-62
  • HY-175294
    PD-L1/Nampt-IN-1

    		PD-1/PD-L1 NAMPT Cancer
    PD-L1/Nampt-IN-1 is an orally active inhibitor that simultaneously target PD-L1 and NAMPT (nicotinamide phosphoribosyltransferase) with IC50s value of 63 nM and 582 nM. PD-L1/Nampt-IN-1 demonstrates cross-species affinity with comparable KD values for hPD-L1 (52.6 nM) and mPD-L1 (49.1 nM), respectively. PD-L1/Nampt-IN-1 effectively inhibits tumor growth by activating the tumor immune microenvironment. PD-L1/Nampt-IN-1 can be used for the study of melanoma .
    PD-L1/Nampt-IN-1

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