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β-coronavirus

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-174350
    CK2-IN-15

    		Casein Kinase SARS-CoV Infection
    CK2-IN-15 (Compound Biv5) is a selective and potent bivalent protein kinase CK2 inhibitor with an IC50 value of 51 pM. CK2-IN-15 significantly reduces the replication of SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells, and also reduces viral replication in an ex vivo model of human nasal epithelial cells. CK2-IN-15 is promising for research of β-coronavirus infection-related diseases .
    CK2-IN-15
  • HY-172906
    SARS-CoV-2 3CLpro-IN-32

    		SARS-CoV Infection
    SARS-CoV-2 3CLpro-IN-32 (compound B16) is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 of 0.109 μM. SARS-CoV-2 3CLpro-IN-32 also exhibits anti-coronavirus HCoV-OC43 activity with an EC50 of 1.99 μM .
    SARS-CoV-2 3CLpro-IN-32

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