Search Result

Results for "

α2B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (15) Adrenergic Receptor (33) Apoptosis (1) CD38 (1) Dopamine Receptor (11) Histamine Receptor (3) Integrin (1) Isotope-Labeled Compounds (3) JAK (2) mAChR (2) Opioid Receptor (1) Reference Standards (2) Sigma Receptor (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (7) Endocrinology (14) Inflammation/Immunology (3) Metabolic Disease (1) Neurological Disease (22)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12709

ARC 239	Adrenergic Receptor 5-HT Receptor	Neurological Disease
ARC 239 is an α2B/C-adrenergic receptor antagonist with pK_i of 7.06 and 6.95 for rat kidney α2B and human α2C, respectively. ARC 239 also inhibits 5-HT1A receptor with a K_i of 63.1 nM ^[2].

HY-12709A

ARC 239 dihydrochloride	Adrenergic Receptor	Cardiovascular Disease Inflammation/Immunology
ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pK_d values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pK_is of 5.6, 8.4, and 7.08, respectively .

HY-160210

BAY-6096	Adrenergic Receptor	Cardiovascular Disease
BAY-6096 is a potent, selective, and highly water-soluble adrenergic receptor *α_2B* antagonist with an IC₅₀ of 14 nM. BAY-6096 can effectively reduceα _2B receptor agonist-induced rat vascular contraction .

HY-100300

AGN 192836	Adrenergic Receptor	Cardiovascular Disease Endocrinology
AGN 192836 is a potent and selective α2 adrenergic agonist with EC₅₀s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.

HY-12709R

ARC 239 (Standard)	Adrenergic Receptor 5-HT Receptor	Neurological Disease
ARC 239 (Standard) is the analytical standard of ARC 239. This product is intended for research and analytical applications. ARC 239 is an α2B/C-adrenergic receptor antagonist with pKi of 7.06 and 6.95 for rat kidney α2B and human α2C, respectively. ARC 239 also inhibits 5-HT1A receptor with a Ki of 63.1 nM ^[2].

HY-101338

RS-79948-197 RS-79948 hydrochloride	Adrenergic Receptor	Neurological Disease
RS-79948-197 is a non-imidazoline *α2-adrenoceptor* antagonist. RS-79948-197 shows K_d values of 0.42 nM, 0.18 nM, 0.19 nM, 0.60 nM, 0.46 nM, and 0.77 nM for rat α2A, rat α2B, rat α2C, human α2A, human α2B, and human α2C, respectively ^[2].

HY-106769B

(3aR,9aR)-Fluparoxan (3aR,9aR)-GR50360	Adrenergic Receptor	Neurological Disease
(3aR,9aR)-Fluparoxan ((3aR,9aR)-GR50360) is a highly selective and potent α2B adrenaline receptor antagonist with the activity of preventing, improving or inhibiting neurodevelopmental disorders and neurodegenerative diseases. As an α2B receptor antagonist, (3aR,9aR)-Fluparoxan can promote the recovery of neurological function. The mechanism of action of (3aR,9aR)-Fluparoxan makes it have important application potential in neuroscience research .

HY-138839

Allyphenyline oxalate	Opioid Receptor	Neurological Disease
Allyphenyline oxalate (compound 9) can enhance the analgesic effect of Morphine. The pKi values of Allyphenyline for α2A, α2B and α2C are 7.24, 6.47 and 7.07, respectively .

HY-U00244

Benzquinamide P2647; BZQ; Benzoquinamide	Adrenergic Receptor	Metabolic Disease Endocrinology
Benzquinamide (P2647) is an antiemetic which can bind to the *α_2A, α_2B, and α_2C* adrenergic receptors (α2-AR) with K_i values of 1,365, 691, and 545 nM, respectively.

HY-101610

OPC-28326	Adrenergic Receptor	Cardiovascular Disease Endocrinology
OPC-28326 is a selective peripheral vasodilator and an angatonist of α2-adrenergic receptor, with K_i of 2040, 285, and 55 nM for α2A-, α2B- and α2C-adrenoceptors, respectively.

HY-153701

JAK-IN-26	JAK	Cancer
JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC₅₀=17.2 nM) .

HY-17416S

Guanfacine-d2 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
Guanfacine-d₂ (hydrochloride) is the deuterium labeled Guanfacine hydrochloride. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors ^[2].

HY-106444A

Fipamezole hydrochloride MPV-1730 hydrochloride; JP-1730 hydrochloride	Adrenergic Receptor	Neurological Disease
Fipamezole hydrochloride is a potent and orally active α2-adrenergic receptor antagonist with K_i values of 9.2 nM, 17 nM, and 55 nM for human α2A, α2B, and α2C, receptors, respectively. Fipamezole hydrochloride is an anti-dyskinetic agent, and can be used for the study of Parkinson's disease .

HY-W042920A

TDIQ hydrochloride	Adrenergic Receptor	Neurological Disease
TDIQ hydrochloride is an analog of Amphetamine with high affinity for α2-adrenergic receptor. TDIQ hydrochloride is a selective α2-adrenoceptor ligand with the K_i values of 75 nM, 95 nM, and 65 nM for α2A-, α2B-, and α2C-adrenergic receptors, respectively .

HY-106444

Fipamezole MPV 1730; JP-1730	Adrenergic Receptor	Neurological Disease
Fipamezole (MPV 1730; JP-1730) is a potent and orally active α2-adrenergic receptor antagonist with K_i values of 9.2 nM, 17 nM, and 55 nM for human α2A, α2B, and α2C, receptors, respectively. Fipamezole is an anti-dyskinetic agent, and can be used for the study of Parkinson's disease .

HY-A0007

Rotigotine Hydrochloride 2 Publications Verification N-0923 Hydrochloride	Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease
Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_i of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-103212

Azepexole dihydrochloride B-HT 933 dihydrochloride; Oxazoloazepin dihydrochloride	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Azepexole (B-HT 933) dihydrochloride is a potent and selective alpha 2-adrenoceptor agonist with pK_is of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively . Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions (IC₅₀= 78.72 nM) ^[2].

HY-15394

(Rac)-Rotigotine hydrochloride N-0437 hydrochloride	Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease Endocrinology
(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_is of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-W741575

Iloperidone carboxylic acid P95-12113	5-HT Receptor Adrenergic Receptor Dopamine Receptor	Neurological Disease
Iloperidone carboxylic acid (P95-12113) is the metabolite of Iloperidone (HY-17410). Iloperidone carboxylic acid exhibits good affinity for 5-HT2A receptor with pK_i of 8.15, and moderate affinity for adrenergic receptor α1/α2B/α2C .

HY-103216

RWJ52353	Adrenergic Receptor	Neurological Disease
RWJ52353 is a selective, orally active ligand for α2D adrenoceptor, which binds α2D, α2A, α2B and α1 receptors, with K_is of 1.5, 254, 621 and 443 nM. RWJ52353 exhibits analgesic efficacy in mouse abdominal irritation test (MAIT), with an ED₅₀ of 15.1 mg/kg .

HY-15394A

(Rac)-Rotigotine N-0437	Adrenergic Receptor 5-HT Receptor Dopamine Receptor	Neurological Disease Endocrinology
(Rac)-Rotigotine (N-0437) is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_is of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-103212A

Azepexole hydrochloride B-HT 933 hydrochloride; Oxazoloazepin hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Azepexole hydrochloride (B-HT 933 dihydrochloride; Oxazoloazepin dihydrochloride) is a selective agonist for α 2-adrenoceptor, with pK_i of 8.3, 7.6, and 7.5 for α2A-, α2B- and α2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions with IC₅₀ of 78.72 nM. Azepexole hydrochloride exhibits antitussive and analgesic efficacy ^[2].

HY-U00244A

Benzquinamide hydrochloride P2647 hydrochloride; BZQ hydrochloride; Benzoquinamide hydrochloride	Adrenergic Receptor	Cancer
Benzquinamide (P2647) is an antiemetic which can bind to the *α_2A, α_2B, and α_2C* adrenergic receptors (α2-AR) with K_i values of 1,365, 691, and 545 nM, respectively. Benzquinamide also inhibits P-glycoprotein mediated drug efflux and potentiates anticancer agent cytotoxicity in multidrug resistant cells ^[2].

HY-153702

JAK-IN-27	JAK	Cancer
JAK-IN-27 (compound 1) is an orally active and potent JAKS family kinase inhibitor with IC₅₀s of 3.0 nM (TYK2), 7.7 nM (JAK1), 629.6 nM (JAK3), respectively. JAK-IN-27 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC₅₀=23.7 nM) .

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) ^[2].

HY-75502

Rotigotine 2 Publications Verification N-0923; (-)-N 0437	Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease Endocrinology
Rotigotine is a potent dopamine receptor agonist with K_i values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research ^[2] .

HY-A0007R

Rotigotine Hydrochloride (Standard) N-0923 Hydrochloride (Standard)	Reference Standards Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease
Rotigotine (Hydrochloride) (Standard) is the analytical standard of Rotigotine (Hydrochloride). This product is intended for research and analytical applications. Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_i of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-15394S1

(Rac)-Rotigotine-d3 hydrochloride N-0437-d₃ hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor Dopamine Receptor 5-HT Receptor	Endocrinology
(Rac)-Rotigotine-d₃ hydrochloride is a deuterium labeled (Rac)-Rotigotine (hydrochloride) (HY-15394). (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_is of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-15394R

(Rac)-Rotigotine hydrochloride (Standard)	Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease Endocrinology
(Rac)-Rotigotine (hydrochloride) (Standard) is the analytical standard of (Rac)-Rotigotine (hydrochloride). This product is intended for research and analytical applications. (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-15394S

(Rac)-Rotigotine-d7 hydrochloride N-0437-d₇ hydrochloride	Isotope-Labeled Compounds Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease Endocrinology
(Rac)-Rotigotine-d₇ (hydrochloride) is deuterium labeled (Rac)-Rotigotine (hydrochloride). (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-75502R

Rotigotine (Standard) N-0923 (Standard); (-)-N 0437 (Standard)	Reference Standards Dopamine Receptor Adrenergic Receptor 5-HT Receptor	Neurological Disease Endocrinology
Rotigotine (Standard) is the analytical standard of Rotigotine. This product is intended for research and analytical applications. Rotigotine is a potent dopamine receptor agonist with K_i values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research ^[2] .

HY-B0371D

(S)-Terazosin	Adrenergic Receptor	Endocrinology
(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity α-adrenoceptor antagonist with K_i values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. (S)-Terazosin also has high-affinity for *α2a, α2B* and *α2c*-adrenoceptor with K_i values of 729 nM, 3.5 nM and 46.4 nM, respectively .

HY-P5846

Muscarinic toxin 3 MT3	mAChR Adrenergic Receptor	Neurological Disease
Muscarinic toxin 3 (MT3) is a potent and non-competitive mAChR and adrenoceptors antagonist with pIC₅₀s of 6.71, 8.79, 8.86, 7.57, 8.13, 8.49, <6.5, 7.29 against M₁, M₄, α_1A, α_1B, α_1D,α_2A,α_2B and α_2C receptors, respectively. Muscarinic toxin 3 displays prominent adrenoceptor activity .

HY-P99744

Modakafusp alfa TAK-573	CD38	Inflammation/Immunology Cancer
Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice ^[2] .

HY-172339

4-AcO-DALT hydrochloride 4-Acetoxy DALT hydrochloride	5-HT Receptor Adrenergic Receptor Dopamine Receptor Histamine Receptor mAChR Sigma Receptor	Neurological Disease
4-AcO-DALT hydrochloride is a tryptamine compound with psychoactive effects. 4-AcO-DALT hydrochloride inhibits 5-HT receptors, alpha receptors, dopamine receptors, histamine receptor 1 (H1), muscarinic M2 receptor and Sigma 2 receptor. 4-AcO-DALT hydrochloride shows K_i values of 582 nM, 2689 nM, 2099 nM, 2116 nM, 958 nM, 137 nM, 824 nM, 479 nM, 406 nM, 874 nM, 4190 nM, 482 nM, 214 nM, 803 nM, 4522 nM, 1907 nM for 5-HT1B, 5-HT1D, 5-HT1E, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT6, 5-HT7A, H1, Sigma 2, α2A, α2B, α2C, D2, D3 receptors ^[2].

HY-117046

AVN-101	5-HT Receptor Histamine Receptor Adrenergic Receptor	Neurological Disease
AVN-101 is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist (K_i of 153 pM), with slightly lesser potency toward 5-HT6, *5-HT2A, and 5HT-2C receptors (K_i* values of 2.04 nM, 1.56 nM, and 1.17 nM, respectively). AVN-101 also exhibits a rather high affinity toward histamine H1 (K_i of 0.58 nM) and adrenergic α2A, *α2B, and α2C* (K_i= 0.41-3.6 nM) receptors. AVN-101 can be studied in such diseases as general anxiety disorders, depression, schizophrenia, Alzheimer’s disease, and multiple sclerosis .

HY-12716

BRL-44408	Adrenergic Receptor	Endocrinology
BRL-44408 is a selective adrenergic receptor antagonist of α2A/α2B AR. BRL-44408 can effectively antagonize the inhibitory effects of norepinephrine or adrenergic receptor agonist Clonidine (HY-12721) on K ⁺-induced [3H]norepinephrine and [3H]5-hydroxytryptamine release. BRL-44408 has a higher affinity for human platelet membranes containing α2A-adrenoceptors than BRL-41992 and Imiloxan (HY-101337). BRL-44408 may affect the release of norepinephrine and 5-hydroxytryptamine through a mechanism mediated by α2A-adrenoceptors, and has a potential role in the regulation of neurotransmitter release .

HY-117046A

AVN-101 hydrochloride	5-HT Receptor Histamine Receptor Adrenergic Receptor	Neurological Disease
AVN-101 hydrochloride is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist (K_i of 153 pM), with slightly lesser potency toward 5-HT6, *5-HT2A, and 5HT-2C receptors (K_i* values of 2.04 nM, 1.56 nM, and 1.17 nM, respectively). AVN-101 hydrochloride also exhibits a rather high affinity toward histamine H1 (K_i of 0.58 nM) and adrenergic α2A, *α2B, and α2C* (K_i= 0.41-3.6 nM) receptors. AVN-101 hydrochloride can be studied in such diseases as general anxiety disorders, depression, schizophrenia, Alzheimer’s disease, and multiple sclerosis .

HY-P99348

Ropeginterferon alfa-2b Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b	Apoptosis	Cancer
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms .

Cat. No.	Product Name	Target	Research Area

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) ^[2].

HY-P5846

Muscarinic toxin 3 MT3	mAChR Adrenergic Receptor	Neurological Disease
Muscarinic toxin 3 (MT3) is a potent and non-competitive mAChR and adrenoceptors antagonist with pIC₅₀s of 6.71, 8.79, 8.86, 7.57, 8.13, 8.49, <6.5, 7.29 against M₁, M₄, α_1A, α_1B, α_1D,α_2A,α_2B and α_2C receptors, respectively. Muscarinic toxin 3 displays prominent adrenoceptor activity .

Cat. No.	Product Name	Target	Research Area

HY-P99744

Modakafusp alfa TAK-573	CD38	Inflammation/Immunology Cancer
Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice ^[2] .

HY-P99348

Ropeginterferon alfa-2b Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b	Apoptosis	Cancer
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms .

Species:	Human (5) Mouse (1)
Tag:	His (3) Tag Free (2) Fc (1)
Source:	HEK293 (3) P. pastoris (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P78672

	*IFN-alpha 2b/IFNA2 Protein, Human (HEK293, Fc)* IFN-alpha 2b; IFNA2B; IFN-alpha 2 (alpha 2b); interferon alpha 2b	Human	HEK293
	IFN-alpha 2a, Human, a cytokine primarily produced by macrophages, displays robust antiviral activities. Its interaction with IFNAR2 is pivotal in mediating essential signaling pathways, contributing to intricate defense mechanisms against viral infections. IFN-alpha 2b/IFNA2 Protein, Human (HEK293, Fc) is the recombinant human-derived IFN-alpha 2b/IFNA2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7023

	*IFN-alpha 2b/IFNA2 Protein, Human* 5 Publications Verification rHuIFN-α2B; IFNA; INFA2; IFN-a 2b	Human	E. coli
	IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8⁺ T cells and induces CD4⁺ T cell depletion. IFN-alpha 2b/IFNA2 Protein, Human contains 165 a.a. (C24-E188), is a protein produced in E. coli with tag free.

HY-P701095

	*IFN-alpha 2b/IFNA2 Protein, Human (His)* rHuIFN-α2B; IFNA; IFNA2; IFN-a 2b	Human	E. coli
	IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8⁺ T cells and induces CD4⁺ T cell depletion. IFN-alpha 2b/IFNA2 Protein, Human contains 165 a.a., is produced in E. coli with N-6*His tagged.

HY-P73246

	*IFN-alpha 2b/IFNA2 Protein, Human (P.pastoris)* 1 Publications Verification Interferon alpha-2; IFN-alpha-2b; LeIF A; IFNA2; IFNA2A	Human	P. pastoris
	IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8⁺ T cells and induces CD4⁺ T cell depletion. IFN-alpha 2b/IFNA2 Protein, Human (P.pastoris) contains 165 a.a., is produced in yeast strain P. pastoris with tag free.

HY-P77716

	*Integrin alpha 2B* beta 3 Protein, Human (HEK293, His)** 1 Publications Verification ITGA2B&ITGB3; ITGA2B; ITGB3	Human	HEK293
	Integrin alpha 2B beta 3 Protein, found on platelets, plays a crucial role in blood clotting. It binds to fibrinogen, facilitating platelet aggregation and forming stable clots. Understanding the functions of Integrin alpha 2B beta 3 Protein can help in developing therapies for clotting disorders and improving hemostasis. Integrin alpha 2B beta 3 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 2B beta 3 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha 2B beta 3 Protein, Human (HEK293, His), has molecular weight of 95-115 kDa.

HY-P700754

	*Integrin alpha 2B* beta 3 Protein, Mouse (HEK293, His)** α2Bβ3; ITGA2B&ITGB3; ITGA2B; ITGB3	Mouse	HEK293
	Integrin α-IIb/β-3 is a multifunctional receptor that recognizes multiple ligands and plays a key role in platelet function and hemostasis. It binds fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin via the RGD sequence, specifically recognizing the HHLGGGAKQAGDV sequence in fibrinogen. Integrin alpha 2B beta 3 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha 2B beta 3 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha 2B beta 3 Protein, Mouse (HEK293, His), has molecular weight of 90-113 kDa.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-15394S1

(Rac)-Rotigotine-d3 hydrochloride

(Rac)-Rotigotine-d₃ hydrochloride is a deuterium labeled (Rac)-Rotigotine (hydrochloride) (HY-15394). (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with K_is of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

HY-17416S

Guanfacine-d2 hydrochloride
Guanfacine-d₂ (hydrochloride) is the deuterium labeled Guanfacine hydrochloride. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors ^[2].

HY-15394S

(Rac)-Rotigotine-d7 hydrochloride

(Rac)-Rotigotine-d₇ (hydrochloride) is deuterium labeled (Rac)-Rotigotine (hydrochloride). (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P86806

	CD41 Antibody (YA6499) antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; GTA antibody; HPA3 antibody; Integrin alpha 2b antibody; Integrin alpha IIb antibody; Integrin alpha-IIb light chain antibody; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody; ITA2B_HUMAN antibody; Itga2b antibody; ITGAB antibody; platelet fibrinogen receptor, alpha subunit antibody; platelet glycoprotein IIb of IIb/IIIa complex antibody; Platelet membrane glycoprotein IIb antibody; platelet specific antigen BAK antibody; PPP1R93 antibody	IHC-P, FC, ICC/IF	Mouse

HY-P86927

	Interferon alpha 2 Antibody (YA6620) Alpha 2a interferon antibody; IFN alpha 2 antibody; IFN alphaA antibody; IFN antibody; IFN-alpha-2 antibody; IFNA antibody; Ifna2 antibody; IFNA2_HUMAN antibody; IFNA2B antibody; Interferon alpha 2a antibody; Alpha 2a interferon antibody; IFN alpha 2 antibody; IFN alphaA antibody; IFN antibody; IFN-alpha-2 antibody; IFNA antibody; Ifna2 antibody; IFNA2_HUMAN antibody; IFNA2B antibody; Interferon alpha 2a antibody; Interferon alpha 2b antibody; Interferon alpha A antibody; Interferon alpha-2 antibody; Interferon alpha-A antibody; Interferon antibody; LeIF A antibody; LeIFA antibody; MGC125764 antibody; MGC125765 antibody	WB, ICC/IF, IHC-P	Human

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: