2. Search Result
Search Result
Results for "

Nedd8

" in MedChemExpress (MCE) Product Catalog:
Recombinant Proteins Recommended:
Species:
Tag:
Source:
Cat. No. Compare Product Name Species Source
  • HY-P70843
    NEDD8 Protein, Human

    Neural precursor cell expressed developmentally down-regulated protein 8; Nedd8; Neddylin; Ubiquitin-like protein Nedd8

    		 Human E. coli
    NEDD8 is an important ubiquitin-like protein that plays a key role in cell cycle regulation and embryogenesis by binding to specific proteins such as cullin and p53/TP53. Its binding to cullin is critical for recruiting E2 enzymes to the cullin-RING-based E3 ubiquitin-protein ligase complex, thereby enabling degradation of regulatory proteins. NEDD8 Protein, Human is the recombinant human-derived NEDD8 protein, expressed by E. coli , with tag free.
  • HY-P71406
    UBE2M Protein, Human

    Nedd8-conjugating enzyme Ubc12; Nedd8 carrier protein; Nedd8 protein ligase; Ubiquitin-conjugating enzyme E2 M; UBC12; UBE2M;

    		Human E. coli
    UBE2M Protein is a crucial mediator in the ubiquitin-like protein NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex, covalently attaching it to target proteins like CUL1, CUL2, CUL3, and CUL4, particularly interacting with the E3 ubiquitin ligase RBX1. This specificity in neddylating specific targets suggests a pivotal role in regulating cellular processes, notably contributing to cell proliferation. UBE2M Protein, Human is the recombinant human-derived UBE2M protein, expressed by E. coli , with tag free.
  • HY-P702529
    APPBP1-UBA3/NEDD8 E1 Protein, Human

    A-116A10.1; amyloid beta precursor protein binding protein 1; amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; APPBP1APP-BP1; Nedd8 activating enzyme E1 subunit 1; Nedd8-activating enzyme E1 regulatory subunit; Nedd8-activating enzyme E1 subunit; protooncogene protein 1; Proto-oncogene protein 1; ula-1

    		 Human E. coli
    The APPBP1-UBA3/NEDD8 E1 protein is the regulatory subunit in the UBA3-NAE1 E1 enzyme complex and activates NEDD8 by adenylating its C-terminal glycine with ATP. This forms the NEDD8-UBA3 thioester, which is transferred to the catalytic cysteine of UBE2M. APPBP1-UBA3/NEDD8 E1 Protein, Human is a recombinant protein dimer complex containing human-derived APPBP1-UBA3/NEDD8 E1 protein, expressed by E. coli , with tag free. APPBP1-UBA3/NEDD8 E1 Protein, Human, has molecular weight of 60 kDa (APP-BP1) 50 kDa (UBA3).
  • HY-P76688A
    UBE2F Protein, Human (His, Solution)

    Nedd8-conjugating enzyme UBE2F; NCE2

    		 Human E. coli
    The UBE2F protein accepts NEDD8 from the UBA3-NAE1 E1 complex and covalently links it to various target proteins in the ubiquitin-like NEDD8 conjugation pathway. The RBX2-UBE2F complex specifically interacts with the E3 ubiquitin ligase RBX2, but not RBX1, for the neddylation of specific targets, especially CUL5. UBE2F Protein, Human (His, Solution) is the recombinant human-derived UBE2F, expressed by E. coli , with N-6*His labeled tag. ,
  • HY-P71290
    SENP8 Protein, Human (His)

    Sentrin-Specific Protease 8; DeNeddylase-1; Nedd8-Specific Protease 1; Protease Cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2

    		 Human E. coli
    SENP8 protein, a pivotal protease in the NEDD8 pathway, plays a dual role in catalyzing the processing of full-length NEDD8 into its mature form and facilitating the deconjugation of NEDD8 from specific target proteins, including cullins and p53. SENP8's dual functionality underscores its crucial role in regulating NEDD8 modification, impacting various cellular pathways and functions. SENP8 Protein, Human (His) is the recombinant human-derived SENP8 protein, expressed by E. coli , with N-6*His labeled tag.

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: