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Itgb5

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  • HY-P77720
    Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi)

    Integrin alpha V beta 5; beta5; alphaV; ITGAV&Itgb5

    		 Human HEK293
    Integrin α V beta 5 proteins, specifically the α-V (ITGAV) subunit, are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences. ITGAV: ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling. Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. Integrin alpha V beta 5 Protein, Human (HEK293, His-Avi), has molecular weight of 85-160 kDa.
  • HY-P700766
    Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi)

    αVβ5; Integrin alpha V beta 5; beta5; alphaV; ITGAV&Itgb5; Integrin alpha V β 5; β5

    		 Human HEK293
    Integrin alpha V beta 5 Proteinas, specifically the alpha-V (ITGAV) subunit, is a versatile receptor for ligands like vitronectin, fibronectin, and others, recognizing the R-G-D sequence. ITGAV:ITGB3 binds fractalkine, acting as a coreceptor in CX3CR1-dependent signaling. It forms crucial interactions with NRG1, FGF1, FGF2, IGF1, IGF2, IL1B, PLA2G2A, FBN1, CD40LG, contributing to diverse pathways. Notably, ITGAV:ITGB3 or ITGAV:ITGB6 is a receptor for TGF-beta-1, mediating its release from LAP and playing a crucial role in TGF-beta-1 activation. Additionally, ITGAV:ITGB5 functions as an Adenovirus type C receptor during microbial infection. Integrin alpha V beta 5's integrative nature underscores its pivotal role in diverse cellular responses and signaling cascades. Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 5 protein, expressed by HEK293, with C-Avi, C-His labeled tag. Integrin alpha V beta 5 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 85-140 kDa.

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