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Isoforms Recommended: Bcl-2
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BCL2

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  • HY-P7537
    BCL2 Protein, Human (His)

    rHuApoptosis Regulator BCL-2, His; B-cell Lymphoma 2; Apoptosis Regulator BCL-2

    		 Human E. coli
    BCL2 Protein regulates the mitochondrial membrane permeability, and inhibits the caspase activity, thereby suppressing the apoptosis in various cell types. BCL2 Protein interacts with BECN1 and AMBRA1, and inhibits the autophagy. BCL2 Protein, Human (His) is the human-derived resombinant BCL2 Protein that is expressed in in E. coli with a His tag at the C-terminus.
  • HY-P75590
    BCL2A1 Protein, Human (His)

    BCL-2-related protein A1; Protein BFL-1; BCL2L5; BFL1; GRS; HBPA1

    		 Human E. coli
    The BCL2A1 protein plays a critical role in resisting apoptosis triggered by IL-3 deprivation, suggesting its importance in the response of hematopoietic cells to external signals and may be involved in protecting endothelial cell survival during infection. It also inhibits serum starvation-induced apoptosis in mammary epithelial cells (HC11). BCL2A1 Protein, Human (His) is the recombinant human-derived BCL2A1 protein, expressed by E. coli , with N-His labeled tag.
  • HY-P7650
    Bcl-2-like protein 1 Protein, Human (His)

    rHuBCL-2-like protein 1, His; BCL-2-Like Protein 1; Apoptosis Regulator BCL-X; BCL2L;

    		Human E. coli
    Bcl-2-like protein 1 Protein, Human (His) is an important apoptosis regulating gene that codes for both an anti-apoptotic (Bcl-xL) and a pro-apoptotic (Bcl-xS) splice variant.
  • HY-P7653
    Bcl-2-like protein 2 Protein, Human (His)

    rHuBCL-2-like protein 2, His; BCL-2-Like Protein 2; Apoptosis Regulator BCL-W; BCL2L2; KIAA0271

    		 Human E. coli
    Bcl-2-like protein 2 is a key regulator that promotes cell survival and prevents dexamethasone-induced apoptosis, which is critical for postmitotic Sertoli cells. It inhibits BAX, emphasizing its role in survival mechanisms. Bcl-2-like protein 2 Protein, Human (His) is the recombinant human-derived Bcl-2-like protein 2 protein, expressed by E. coli , with C-6*His labeled tag.
  • HY-P700303
    Bcl-2-like Protein 11 Protein, Human (His)

    rHuBCL-2-like Protein 11, His; BCL-2-like protein 11; BIML

    		 Human E. coli
    Bcl-2-like protein 11 (BCL2L11), despite its classification, does not interact with humanin. This unique feature distinguishes BCL2L11 from expected protein-protein interactions typically associated with Bcl-2 family members. Bcl-2-like Protein 11 Protein, Human (His) is the recombinant human-derived Bcl-2-like Protein 11 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P7651
    Bax Protein, Human (His)

    rHuBCL2L4, His; Apoptosis Regulator BAX; BCL-2-Like Protein 4; BCL2L4; BAX

    		 Human E. coli
    Bax Protein, Human (His) suppresses tumorigenesis and stimulates apoptosis. BCL2L4 (BAX) is the proapoptotic members of the Bcl-2 family that are ubiquitously expressed in different tissues.
  • HY-P702614
    Bax Protein, Human (Cell-Free, His)

    rHuBCL2L4, His; Apoptosis Regulator BAX; BCL-2-Like Protein 4; BCL2L4; BAX

    		 Human E. coli Cell-free
    Bax Protein, Human (Cell-Free, His) is the recombinant human-derived Bax, expressed by E. coli Cell-free , with N-10*His labeled tag.
  • HY-P76165
    BCL2L12 Protein, Human (GST)

    BCL-2-like protein 12; BCL2-L-12; BCL-2-related proline-rich protein; BPR

    		 Human E. coli
    BCL2-like 12 (BCL2L12) is a new member of the apoptosis-related BCL2 gene family. BCL2L12 contains a highly conserved BH2 domain, a BH3-like domain and a proline-rich region. BCL2L12 exhibits pro-apoptotic activity in breast tumor and gastric cancer. BCL2L12 is an inhibitor of post-mitochondrial effector caspase activation, as it binds to and inhibits caspase-7 and upregulates the caspase-3-specific inhibitor 伪B-crystallin (CRYAB). BCL2L12 attenuates endogenous p53-directed transcriptomic changes after genotoxic stress and inhibits p53-dependent DNA damage-induced apoptosis. BCL2L12 Protein, Human (GST) is the recombinant human-derived BCL2L12 protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P75473
    BMF Protein, Human (His)

    BCL-2-modifying factor; BMF

    		 Human E. coli
    BMF proteins may play a key role in apoptosis, with isoform 1 being the major promoter. It interacts with anti-apoptotic proteins (including MCL1, BCL2, BCL2L1/BCL-Xl, BCL2A1 and BCL2L2/BCL-w), suggesting involvement in the regulatory network of cell death. BMF Protein, Human (His) is the recombinant human-derived BMF protein, expressed by E. coli , with N-His labeled tag.
  • HY-P702954
    BAD Protein, Human (His, Myc)

    BBC6; BCL2L8

    		 Human E. coli
    BAD Protein, Human (His, Myc) is the recombinant human-derived BAD, expressed by E.coli , with His, Myc labeled tag.
  • HY-P703089
    BAK1 Protein, Human

    BAK; BCL2L7; CDN1

    		 Human E. coli
    BAK1 Protein, Human is the recombinant human-derived BAK1, expressed by E. coli , with tag Free labeled tag.
  • HY-P7647
    BAG-2 Protein, Human (His)

    rHuBAG2, His; BAG Family Molecular Chaperone Regulator 2; BAG-2; BCL-2-Associated Athanogene 2; BAG2

    		 Human E. coli
    BAG2 Protein, Human (His) promotes tumorigenesis through enhancing mutant p53 protein levels and function. BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21CIP1 pathway.
  • HY-P7670
    BNIP3/NIP3 Protein, Human (His)

    rHuBNIP3, His; BNIP3; NIP3; BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3

    		 Human E. coli
    BNIP3/NIP3 Protein, Human (His) expresses in E. coliwith a His tag. BNIP3 belongs to the Bcl-2 protein family that regulates programmed cell death.
  • HY-P75471
    BNIP3L Protein, Human

    BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; NIP3L; BNIP3L; BNIP3A; BNIP3H; NIX

    		 Human E. coli
    BNIP3L, a pro-apoptotic member of the Bcl-2 family, possesses a BH3 domain and binds to Bcl-2. It directly targets mitochondria, inducing apoptotic changes like membrane potential loss and cytochrome c release. With ubiquitous expression, especially in fat and ovary, the gene suggests involvement in diverse physiological processes across multiple organs, emphasizing its potential significance. BNIP3L Protein, Human is the recombinant human-derived BNIP3L protein, expressed by E. coli , with tag free.

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