2. Recombinant Proteins
  3. Enzymes & Regulators
  4. BAD Protein, Human (His, Myc)

BAD Protein, Human (His, Myc) is the recombinant human-derived BAD, expressed by E.coli, with His, Myc labeled tag.

For research use only. We do not sell to patients.

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Description

BAD Protein, Human (His, Myc) is the recombinant human-derived BAD, expressed by E.coli, with His, Myc labeled tag.
Background

Bad is a protein that promotes cell death. It successfully competes for binding to Bcl-X(L), Bcl-2, and Bcl-W, thereby influencing the heterodimerization levels of these proteins with BAX. Bad can reverse the death repressor activity of Bcl-X(L) but not that of Bcl-2 (By similarity). Additionally, it appears to act as a link between growth factor receptor signaling and apoptotic pathways.
Species

Human
Source

E. coli
Tag

N-10*His;C-Myc
Accession

Q92934 (E30-E234)
Gene ID

572
Protein Length

partial
Synonyms
BBC6; BCL2L8
Predicted Molecular Mass
30.4 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Documentation
Handling Instructions (2659 KB)

BAD Protein, Human (His, Myc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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BAD Protein, Human (His, Myc)
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HY-P702954
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