2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Platelet-activating Factor Receptor (PAFR) Histamine Receptor
  4. Sch-40338

Sch-40338 is a dual antagonist of platelet-activating factor (PAF) and histamine with an IC50 of 0.59 μM (PAF-induced platelet aggregation) and a Ki of 5.4 μM (Histamine H₁ receptor binding). Sch-40338 can be used for the study of allergic disease.

For research use only. We do not sell to patients.

Sch-40338

Sch-40338 Chemical Structure

CAS No. : 117796-62-0

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Sch-40338 Related Antibodies

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Description

Sch-40338 is a dual antagonist of platelet-activating factor (PAF) and histamine with an IC50 of 0.59 μM (PAF-induced platelet aggregation) and a Ki of 5.4 μM (Histamine H₁ receptor binding). Sch-40338 can be used for the study of allergic disease[1].

Molecular Weight

355.86

Formula

C20H22ClN3O
CAS No.
SMILES

CC(N1CCN(CC1)C2C3=CC=C(C=C3CCC4=CC=CN=C24)Cl)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Sch-40338 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sch-40338117796-62-0Sch40338Sch 40338Platelet-activating Factor Receptor (PAFR)Histamine ReceptorHistamine H1-receptor antagonist?Conformational analysis?Molecular modeling?Rigid analoguesInhibitorinhibitorinhibit

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