2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. (S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride  (Synonyms: SCH-23388 hydrochloride)

Cat. No.: HY-19545B
Handling Instructions Technical Support

(S)-SCH-23390 (hydrochloride) is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively).

For research use only. We do not sell to patients.

(S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride Chemical Structure

CAS No. : 1217443-99-6

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Other Forms of (S)-SCH-23390 hydrochloride:

(S)-SCH-23390 hydrochloride Related Antibodies

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Description

(S)-SCH-23390 (hydrochloride) is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively)[1].

In Vivo

(S)-SCH-23390 (0.05-15.5 mg/kg, i.p., single dose) (hydrochloride) results in no significant reduction of the cerebrospinal fluid (CSF) in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male SD rats (140-200 g)[1]
Dosage: 0.05, 0.5, 5.0 and 15.5 mg/kg
Administration: i.p., single dose
Result: Did not significantly reduce the net production of CSF at any dose between 0.05 and 15.5 mg/kg.
Molecular Weight

324.24

Formula

C17H19Cl2NO
CAS No.
SMILES

OC1=C(Cl)C=C2CCN(C)C[C@@H](C3=CC=CC=C3)C2=C1.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(S)-SCH-23390 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-SCH-233901217443-99-6SCH-23388SCH23388SCH 23388Dopamine ReceptorS-enantiomerCSFratSCH-23390Inhibitorinhibitorinhibit

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