1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. Calcium Channel P-glycoprotein
  3. S 16317

S 16317 is an orally active dihydropyridine derivative with low calcium channel affinity (Ki: 0.55 μM). S 16317 inhibits P-gp mediated efflux of ADR. S 16317 overcomes multidrug resistance in tumor.

For research use only. We do not sell to patients.

S 16317

S 16317 Chemical Structure

CAS No. : 151489-04-2

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Description

S 16317 is an orally active dihydropyridine derivative with low calcium channel affinity (Ki: 0.55 μM). S 16317 inhibits P-gp mediated efflux of ADR. S 16317 overcomes multidrug resistance in tumor[1].

Molecular Weight

578.48

Formula

C28H33Cl2N3O6

CAS No.
SMILES

O=C(OC)C1=C(NC(COCCOCCNCC2=CC=NC=C2)=C(C1C3=C(Cl)C(Cl)=CC=C3)C(OCC)=O)C

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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S 16317
Cat. No.:
HY-120790
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