2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. RPR 130737

RPR 130737 is a selective, potent and competitive inhibitor for factor Xa with a Ki of 2.4 nM. RPR 130737 shows selectivity of more than 1000-fold over thrombin, activated protein C, plasmin, tissue-plasminogen activator and trypsin. RPR 130737 can prolong plasma activated partial thromboplastin time and prothrombin time. RPR 130737 shows no effect on platelet aggregation. RPR 130737 can be used for the research of cardiovascular disease, such as thrombosis.

For research use only. We do not sell to patients.

RPR 130737

RPR 130737 Chemical Structure

CAS No. : 205054-36-0

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Description

RPR 130737 is a selective, potent and competitive inhibitor for factor Xa with a Ki of 2.4 nM. RPR 130737 shows selectivity of more than 1000-fold over thrombin, activated protein C, plasmin, tissue-plasminogen activator and trypsin. RPR 130737 can prolong plasma activated partial thromboplastin time and prothrombin time. RPR 130737 shows no effect on platelet aggregation. RPR 130737 can be used for the research of cardiovascular disease, such as thrombosis[1].

Molecular Weight

471.55

Formula

C21H21N5O4S2
CAS No.
SMILES

O=C(N(CC1=CC(C(N)=N)=CC=C1O)CC2)[C@H]2NS(=O)(C3=CC=C(C4=CN=CC=C4)S3)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RPR 130737 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RPR 130737205054-36-0RPR130737RPR-130737Factor XaFxafactor Xathrombinactivated protein Cplasmintissue-plasminogen activatortrypsinthromboplastin timeprothrombin timeplatelet aggregationthrombosisInhibitorinhibitorinhibit

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