2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Hydrolases (EC 3)
  5. PTPRM Protein, Human (GST)

PTPRM Protein, Human (GST) is the recombinant human-derived PTPRM, expressed by E. coli , with N-GST labeled tag. ,

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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Description

PTPRM Protein, Human (GST) is the recombinant human-derived PTPRM, expressed by E. coli , with N-GST labeled tag. ,
Background

PTPRM is a receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and regulates adipogenic differentiation by modulating p120 catenin (CTNND1) phosphorylation. It promotes CTNND1 dephosphorylation to prevent its cytoplasmic localization (which normally inhibits SLC2A4 membrane trafficking), thereby directing the glucose transporter SLC2A4 to the plasma membrane for proper glucose transport function.
Species

Human
Source

E. coli
Tag

N-GST
Accession

P28827-1 (E896-N1175)
Gene ID

5797
Molecular Construction
N-term
GST
PTPRM (E896-N1175)
Accession # P28827-1
C-term
Protein Length

Partial
Synonyms
PTPRL1; PTPµ
Predicted Molecular Mass
56.2 kDa
Molecular Weight

Approximately 55-60 kDa,based on SDS-PAGE under reducing conditions.
Purity

Greater than 80% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PTPRM Protein, Human (GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PTPRM Protein, Human (GST)
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