MPIF-1/CCL23 Protein, Human (99a.a, HEK293, His)

MPIF-1/CCL23 Protein, Human (99a.a, HEK293, His) is the recombinant human-derived MPIF-1/CCL23 protein, expressed by HEK293, with N-His tag.

CCL23 exhibits chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not activated lymphocytes. It inhibits the proliferation of myeloid progenitor cells in colony formation assays and can bind both heparin and CCR1. The truncated forms CCL23(19-99), CCL23(22-99), CCL23(27-99), and CCL23(30-99) show stronger chemoattractant potency than full-length CCL23. by similar: Other chemokines like CCL3 and CCL5 also signal through CCR1, though their target cell profiles may differ.

Human

HEK293

N-His

P55773-1 (R22-N120)

6368

Approximately 12-17 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from 0.22 μm filtered solution of PBS, pH7.4 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.