2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. CC Chemokines
  6. CCL21
  7. Exodus-2/CCL21 Protein, Human (Sf9, His)

Exodus-2/CCL21 Protein, Human (Sf9, His) is the recombinant human-derived Exodus-2/CCL21 protein, expressed by sf9 insect cells, with C-His tag.

For research use only. We do not sell to patients.

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Description

Exodus-2/CCL21 Protein, Human (Sf9, His) is the recombinant human-derived Exodus-2/CCL21 protein, expressed by sf9 insect cells, with C-His tag.
Background

CCL21 is a chemokine that inhibits hematopoiesis and stimulates chemotaxis. In vitro, it exhibits chemotactic activity for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. This chemokine shows preferential activity towards naive T-cells and may play a role in mediating lymphocyte homing to secondary lymphoid organs. CCL21 binds to the atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Species

Human
Source

sf9 insect cells
Tag

C-His
Accession

O00585 (S24-P134)
Gene ID

6366
Molecular Construction
N-term
CCL21 (S24-P134)
Accession # O00585
His
C-term
Synonyms
rHuExodus-2/CCL21; C-C motif chemokine 21; SLC; SCYA21
Predicted Molecular Mass
14.1 kDa.
Molecular Weight

17-19 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Exodus-2/CCL21 Protein, Human (Sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Exodus-2/CCL21 Protein, Human (Sf9, His)
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