2. Membrane Transporter/Ion Channel
  3. GLUT
  4. Rapaglutin A

Rapaglutin A is a glucose transporter (GLUT) inhibitor. Rapaglutin A is a pan-GLUT inhibitor of Class I isoforms GLUT1, GLUT3, and GLUT4 with an IC50 of 12 nM. Rapaglutin A has an inhibitory effect on A549 proliferation.

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Rapaglutin A Chemical Structure

Rapaglutin A Chemical Structure

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Rapaglutin A Related Antibodies

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Description

Rapaglutin A is a glucose transporter (GLUT) inhibitor. Rapaglutin A is a pan-GLUT inhibitor of Class I isoforms GLUT1, GLUT3, and GLUT4 with an IC50 of 12 nM. Rapaglutin A has an inhibitory effect on A549 proliferation[1].

Molecular Weight

1178.41

Formula

C64H87N7O14
SMILES

COC(C=C1CC[C@@H]2C3=CC=CC(NC(CCC(N([C@H](C(N[C@@H](C(N([C@@](C(NCC(N(CC/C=C/C(OCC(C)(C(C(N4[C@](CCCC4)([H])C(O2)=O)=O)=O)C)=O)C)=O)=O)([H])[C@H](C)CC)C)=O)CC5=CC=CC=C5)=O)CC(C)C)C)=O)=O)=C3)=C(C=C1)OC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Rapaglutin A Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rapaglutin ARgA JW11-D2GLUTGlucose transporterglucose transporter (GLUT)A549pan-GLUTInhibitorinhibitorinhibit

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