2. Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Apoptosis Reactive Oxygen Species (ROS)
  4. R24

R24 is a type of flavonoid derivative. R24 exhibits strong anti-angiogenic and anti-proliferative effects. R24 induces cell apoptosis and promotes the production of reactive oxygen species (ROS). R24 can be used for the study of cancers such as lung cancer and colorectal cancer.

For research use only. We do not sell to patients.

R24

R24 Chemical Structure

CAS No. : 151417-66-2

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R24 Related Antibodies

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Description

R24 is a type of flavonoid derivative. R24 exhibits strong anti-angiogenic and anti-proliferative effects. R24 induces cell apoptosis and promotes the production of reactive oxygen species (ROS). R24 can be used for the study of cancers such as lung cancer and colorectal cancer[1].
In Vitro

R24 inhibits A549, AsPC-1, HCT-116, and PC-3 cell lines with IC50s of 3.44, 3.59, 1.22, and 11.83 μM, respectively[1].
R24 (2.5 μM, 48 h) induces A549 cells apoptosis and increases cell accumulation in the sub-G1 phase[1].
R24 (2.5-10 μM, 30 min) promotes intracellular ROS production in a dose-dependent manner in A549 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

R24 Related Antibodies

Apoptosis Analysis[1]

Cell Line: A549 cells
Concentration: 2.5 μM
Incubation Time: 48 h
Result: Increased early and late apoptosis rate.

Cell Cycle Analysis[1]

Cell Line: A549 cells
Concentration: 2.5 μM
Incubation Time: 48 h
Result: Increased cell accumulation in the sub-G1 phase.
In Vivo

R24 (60 μg/egg, 48 h) disrupts angiogenesis in chicken embryos[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

340.33

Formula

C19H16O6
CAS No.
SMILES

O=C1C2=CC=C(C=C2OC3=CC(OCC4OC4)=CC=C31)OCC5OC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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R24 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

R24151417-66-2R 24R-24ApoptosisReactive Oxygen Species (ROS)FlavonoidAngiogenesisReactive oxygen species,Tumor vasculatureInhibitorinhibitorinhibit

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