2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. C Chemokines

C Chemokines

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The C-chemokine subfamily (γ-chemokines) lacks the first and third cysteines, and thus has only hemocysteine residues in the conserved region. This family is composed of two members, XCL1 (also known as lymphotactin/Ltn/ATAC/SCYC-1/SCM1-α) and XCL2 (SCM1-β/SCYC-2). XCL1 and XCL2 are produced by activated NK cells, CD8 T cells, γδ T cells, and NK T cells. Structurally, XCL2 and XCL1 are similar, and under physiological NaCl and temperature conditions, the folding structure of monomer chemokines and the unrelated dimer state switch between[1].

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7234
    Lymphotactin/XCL1 Protein, Human

    rHuLymphotactin/XCL1; ATAC; SCYC1

    		Human E. coli
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His) is produced in E. coli, and consists of 92 amino acids (G23-G114).
  • HY-P71947A
    XCL1 Protein, Rat (His)

    Xcl1; Ltn; Scyc1; Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Small-inducible cytokine C1

    		Rat E. coli
    XCL1 protein attracts lymphocytes but not monocytes or neutrophils. It plays a crucial role in accumulating dendritic cells in the thymus medulla and contributes to regulatory T cell development, establishing self-tolerance. XCL1 Protein, Rat (His) is the recombinant rat-derived XCL1 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P74461
    XCL2/SCM-1 beta Protein, Human (sf9, His)

    Cytokine SCM-1 beta; C motif chemokine 2; XCL2; SCYC2

    		Human Sf9 insect cells
    XCL2 (also knowns as SCM1-β and SCYC-2) is a member of C chemokine sub-family that is highly related to XCL1. XCL2 binds and activates the G protein-coupled receptor, XCR1. XCL2 is mainly produced by activated T cells and natural killer cells. XCL2/SCM-1 beta Protein, Human (sf9, His) is produced in sf9 insect cells with a C-Terminal His-tag. It consists of 114 amino acids (M1-G114).
  • HY-P71434
    Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His)

    Lymphotactin; ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1; LTN; SCYC1 and XCL1

    		Human HEK293
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Human (HEK293, Fc-His) is produced in HEK293 cells with six C-Terminal His-tags and a C-Terminal Fc-tag. It consists of 93 amino acids (V22-G114).
  • HY-P77071
    Lymphotactin/XCL1 Protein, Canine (sf9, His)

    ATAC; C motif chemokine 1; Cytokine SCM-1; SCM-1-alpha; LTN; SCYC1

    		Canine Sf9 insect cells
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Canine (sf9, His) is produced in sf9 cells with a C-Terminal His-tag.
  • HY-P77072
    Lymphotactin/XCL1 Protein, Cynomolgus (sf9, His)

    ATAC; C motif chemokine 1; Cytokine SCM-1; SCM-1-alpha; LTN; SCYC1

    		Cynomolgus Sf9 insect cells
    XCL1, a C class chemokine also known as Lymphotactin, is mainly produced by activated CD8+ T cells and natural killer cells. XCL1 signals by binding to the XCR1 receptor. XCL1 is involved in infectious, inflammatory and immunological diseases. Lymphotactin/XCL1 Protein, Cynomolgus (sf9, His) is produced in sf9 cells with a C-Terminal His-tag.
  • HY-P704077
    Lymphotactin/XCL1 Protein, Mouse

    Xcl1; Lptn; Ltn; Scyc1; Lymphotactin; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; Small-inducible cytokine C1

    		Mouse E. coli
    The XCL1 protein selectively attracts lymphocytes and its chemotactic effects are distinct from those of monocytes or neutrophils. XCL1 is critical in the thymus, where it mediates the accumulation of dendritic cells in the medulla and contributes significantly to the development of regulatory T cells and the establishment of self-tolerance. Lymphotactin/XCL1 Protein, Mouse is the recombinant mouse-derived Lymphotactin/XCL1 protein, expressed by E. coli, with tag free.
Cat. No. Product Name Effect Purity