2. PROTAC Cell Cycle/DNA Damage
  3. PROTACs Deubiquitinase
  4. PROTAC USP7 Degrader-1

PROTAC USP7 Degrader-1 (Compound 40) is a ubiquitin-specific protease 7 (USP7) PROTAC degrader with a DC50 of 25 nM. PROTAC USP7 Degrader-1 can be used for cancers like acute myeloid leukemia (AML) research. Pink: USP7 ligand (HY-175359); Blue: VHL ligase ligand (HY-112078); Black: linker

For research use only. We do not sell to patients.

PROTAC USP7 Degrader-1

PROTAC USP7 Degrader-1 Chemical Structure

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PROTAC USP7 Degrader-1 Related Antibodies

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Description

PROTAC USP7 Degrader-1 (Compound 40) is a ubiquitin-specific protease 7 (USP7) PROTAC degrader with a DC50 of 25 nM. PROTAC USP7 Degrader-1 can be used for cancers like acute myeloid leukemia (AML) research[1]. Pink: USP7 ligand (HY-175359); Blue: VHL ligase ligand (HY-112078); Black: linker

IC50 & Target[1]

USP7

25 nM (DC50)

Molecular Weight

1183.51

Formula

C64H86N12O8S
SMILES

O=C([C@H]1N(C([C@@H](NC(CCCCCOC2=CC=C(C3=C(C4=NN3C)N=CN(CC5(O)CCN(C(C[C@@H](C)C6=CC=CC=C6)=O)CC5)C4=O)C=C2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C7=CC=C(C8=C(N9CCN(CCN(C)C)CC9)N=CS8)C=C7)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC USP7 Degrader-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC USP7 Degrader-1PROTACsDeubiquitinaseDUBsPROTACDegradationubiquitin-specific protease 7USP7VHLOCI-AML5 cellsMM.1S cellsHEK 293 cellsAMLInhibitorinhibitorinhibit

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