2. Apoptosis MAPK/ERK Pathway Stem Cell/Wnt
  3. Apoptosis p38 MAPK Bcl-2 Family Caspase Raf MEK ERK
  4. PQ-1

PQ-1 is a gap junction enhancer.

For research use only. We do not sell to patients.

PQ-1

PQ-1 Chemical Structure

CAS No. : 955995-48-9

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Other Forms of PQ-1:

PQ-1 Related Antibodies

Top Publications Citing Use of Products

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim BNIP3

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Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

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B-Raf C-Raf Raf

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MEK1 MEK2 MEK5 MEK MAP2K4/MEK4

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ERK ERK1 ERK2 ERK5 ERK8

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Description

PQ-1 is a gap junction enhancer. PQ-1 activates p44/42 MAPK, increases phosphorylated p38-MAPK, reduces Bcl-2 expression, increases the cleavage of pro-caspase-3. PQ-1 affects the Raf-MEK-ERK cascade, induces Apoptosis. PQ-1 can be used in the research of breast cancer[1].

Molecular Weight

405.41

Formula

C21H22F3N3O2
CAS No.
SMILES

NCCCNC1=C2C(C(C)=CC=N2)=C(OC3=CC=CC(C(F)(F)F)=C3)C(OC)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PQ-1 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PQ-1955995-48-9PQ1PQ 1Apoptosisp38 MAPKBcl-2 FamilyCaspaseRafMEKERKRaf kinasesMitogen-activated protein kinase kinaseMAPKKMAP2KExtracellular signal regulated kinasesbreast cancerFMC2uInhibitorinhibitorinhibit

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