2. PROTAC
  3. Ligands for E3 Ligase
  4. Pomalidomide 7'OMe

Pomalidomide 7'OMe is a E3 ligase ligand that can be used in the recruitment of CRBN protein. Pomalidomide 7'OMe can be connected to the BRD9 ligand (HY-107446) by a linker to synthesis of PROTAC BRD9 degrader-9 (HY-177729).

For research use only. We do not sell to patients.

Pomalidomide 7'OMe

Pomalidomide 7'OMe Chemical Structure

CAS No. : 2154355-10-7

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Pomalidomide 7'OMe Related Antibodies

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View All Ligands for E3 Ligase Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21

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Description

Pomalidomide 7'OMe is a E3 ligase ligand that can be used in the recruitment of CRBN protein. Pomalidomide 7'OMe can be connected to the BRD9 ligand (HY-107446) by a linker to synthesis of PROTAC BRD9 degrader-9 (HY-177729)[1].

IC50 & Target[1]

Cereblon

 

Molecular Weight

303.27

Formula

C14H13N3O5
CAS No.
SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C(OC)=CC=C3N)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pomalidomide 7'OMe Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide 7'OMe2154355-10-7Ligands for E3 LigaseE3 ligase-recruiting MoietyCRBNBRD9E3 ligasecancerInhibitorinhibitorinhibit

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