2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. PF-00446687 hydrochloride

PF-00446687 hydrochloride is a potent, brain-penetrating, selective melanocortin 4 receptor (MC4R) agonist with an EC50 of 12 nM. PF-00446687 hydrochloride can be used in the research of sexual dysfunction.

For research use only. We do not sell to patients.

PF-00446687 hydrochloride

PF-00446687 hydrochloride Chemical Structure

CAS No. : 862282-10-8

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PF-00446687 hydrochloride Related Antibodies

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Description

PF-00446687 hydrochloride is a potent, brain-penetrating, selective melanocortin 4 receptor (MC4R) agonist with an EC50 of 12 nM. PF-00446687 hydrochloride can be used in the research of sexual dysfunction[1][2].

IC50 & Target[1][2]

MC4R

12 nM (EC50)

Molecular Weight

507.06

Formula

C28H37ClF2N2O2
CAS No.
SMILES

O=C(N1C[C@H]([C@@]([C@H](C1)C)(C2=CC=CC=C2)O)C)[C@H]3[C@H](C4=C(C=C(C=C4)F)F)CN(C3)C(C)(C)C.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-00446687 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-00446687862282-10-8PF00446687PF 00446687Melanocortin ReceptorMC Receptorsexual dysfunctionInhibitorinhibitorinhibit

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PF-00446687 hydrochloride
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