2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. PARP1-IN-39

PARP1-IN-39 is an inhibitor of PARP1 with an IC50 of 0.22 nM. PARP1-IN-39 has an IC50 of 1.57 nM in human breast cancer cells. PARP1-IN-39 can be studied in breast, ovarian, pancreatic, and prostate cancers associated with DNA repair deficiencies, such as BRCA1/2 mutations.

For research use only. We do not sell to patients.

PARP1-IN-39 Chemical Structure

PARP1-IN-39 Chemical Structure

CAS No. : 3054988-47-2

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PARP1-IN-39 Related Antibodies

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Description

PARP1-IN-39 is an inhibitor of PARP1 with an IC50 of 0.22 nM. PARP1-IN-39 has an IC50 of 1.57 nM in human breast cancer cells. PARP1-IN-39 can be studied in breast, ovarian, pancreatic, and prostate cancers associated with DNA repair deficiencies, such as BRCA1/2 mutations[1].

Molecular Weight

508.46

Formula

C24H19F3N8O2
CAS No.
SMILES

CCNC(C1=CC=C(N2C=C3CN(CC3=N2)CC4=C(C5=C(N6N=CC(F)=C6C(N5)=O)C=C4)F)C(F)=N1)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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PARP1-IN-39 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PARP1-IN-393054988-47-2PARPpoly ADP ribose polymeraseInhibitorinhibitorinhibit

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