1. Cell Cycle/DNA Damage
  2. Poly(ADP-ribose) Glycohydrolase (PARG)
  3. PARG-IN-7

PARG-IN-7 (Example 38) is a Poly ADP-ribose glycohydrolase (PARG) inhibitor (IC50: < 0.1 μM). PARG-IN-7 inhibits cell viability of HCC1806-XRCC1 KD (knock down) cells with an IC50 < 1 μM. PARG-IN-7 can be used for cancer research.

For research use only. We do not sell to patients.

PARG-IN-7

PARG-IN-7 Chemical Structure

CAS No. : 2632343-19-0

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Description

PARG-IN-7 (Example 38) is a Poly ADP-ribose glycohydrolase (PARG) inhibitor (IC50: < 0.1 μM). PARG-IN-7 inhibits cell viability of HCC1806-XRCC1 KD (knock down) cells with an IC50 < 1 μM. PARG-IN-7 can be used for cancer research[1].

Molecular Weight

550.60

Formula

C22H24F2N8O3S2

CAS No.
SMILES

N#CC1(CC1)NS(=O)(C2=CC(N3CCN(CC3)C(C(C)C)=O)=C(C=NN4C5=NN=C(C(F)F)S5)C4=C2)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PARG-IN-7
Cat. No.:
HY-171789
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