2. Protein Tyrosine Kinase/RTK
  3. FLT3
  4. MolPort-002-705-878

MolPort-002-705-878 is a highly selective FMS-like tyrosine kinase 3 (FLT3) inhibitor with a binding affinity of −11.33 kcal/mol. MolPort-002-705-878 inhibits the proliferation of FLT3-mutated acute myeloid leukemia (AML) cells. MolPort-002-705-878 is promising for research of FLT3-mutated AML.

For research use only. We do not sell to patients.

MolPort-002-705-878

MolPort-002-705-878 Chemical Structure

CAS No. : 304480-98-6

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Description

MolPort-002-705-878 is a highly selective FMS-like tyrosine kinase 3 (FLT3) inhibitor with a binding affinity of −11.33 kcal/mol. MolPort-002-705-878 inhibits the proliferation of FLT3-mutated acute myeloid leukemia (AML) cells. MolPort-002-705-878 is promising for research of FLT3-mutated AML[1].

Molecular Weight

424.25

Formula

C20H14BrN3O3
CAS No.
SMILES

CC1=CC2=C(NC(/C2=N/NC(C3=C(C=C4C=CC=CC4=C3)O)=O)=O)C=C1Br
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MolPort-002-705-878 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MolPort-002-705-878304480-98-6FLT3Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3AMLInhibitorinhibitorinhibit

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