2. Academic Validation
  3. Tumor Diagnosis and Treatment Based on Stimuli-Responsive Aggregation of Gold Nanoparticles

Tumor Diagnosis and Treatment Based on Stimuli-Responsive Aggregation of Gold Nanoparticles

  • Exploration (Beijing). 2025 Feb 6;5(3):270006. doi: 10.1002/EXP.70006.
Xiaowei Chang 1,  Huaiyu Wang 2,  Xin Chen 1
Affiliations

Affiliations

  • 1 Department of Chemical Engineering, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, School of Chemical Engineering and Technology Xi'an Jiaotong University Xi'an China.
  • 2 The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
PMID: 40585773 DOI: 10.1002/EXP.70006
Abstract

Gold nanomaterials have been used in the diagnosis and treatment of different tumors due to their unique physical and chemical properties. Among them, gold nanoparticles with stimuli-responsive aggregation functions have attracted extensive attention because they can meet the unique needs of tumor diagnosis and treatment at different stages through structural changes. However, how to effectively modify gold nanoparticles to achieve structural transformation for specific stimuli, and the role of corresponding structural transformation in improving the effect of diagnosis and treatment still lack systematic summary. In this review, we comprehensively summarized the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment.

Keywords

gold nanoparticles; stimuli‐responsive aggregation; tumor diagnosis and treatment.

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