2. Academic Validation
  3. Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

  • Chem Biodivers. 2025 Jul;22(7):e202403067. doi: 10.1002/cbdv.202403067.
Doaa Hammad 1 2,  El-Mahdi Ourhzif 3 4,  Salha Hamri 2,  Hafid Abderrafia 2,  Mostafa Khouili 2,  Maria Dolors Pujol 1
Affiliations

Affiliations

  • 1 Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.
  • 2 Laboratory of Molecular Chemistry, Materials and Catalysis, Faculty of Science and Technology, Sultan Moulay Slimane University, Beni-Mellal, Morocco.
  • 3 Centre de recherche du Centre hospitalier de l'Université de Montréal, Montréal, Québec, Canada.
  • 4 Département de Pharmacologie et physiologie, Faculté de Médecine, Université de Montréal, Québec, Canada.
PMID: 39977586 DOI: 10.1002/cbdv.202403067
Abstract

A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of Other new products with Anticancer, antioxidant, antidiuretic, and antimalarial effects. Despite the huge number of existing drugs, Plants are still used mainly as a treatment for pain and as a source of inspiration for new drugs. In this study, the different components of the dried latex of this plant and their effects on human health have been studied. It should be noted that resiniferatoxin, with a pain-relieving activity superior to capsaicin, has proven to be effective for the treatment of osteoarthritis, a painful disease with no specific treatment.

Keywords

Euphorbia resinifera; Euphorbiaceae; antibacterial; antitumor; anti‐inflammatory activities; cytotoxicity; ethnomedicinal uses; latex; osteoarthritis; resiniferatoxin.

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