2. Academic Validation
  3. New alkaloids from the leaves of Evodia rutaecarpa

New alkaloids from the leaves of Evodia rutaecarpa

  • Nat Prod Res. 2016 Oct;30(19):2154-9. doi: 10.1080/14786419.2016.1146888.
Xiao Xia 1,  Jian-Guang Luo 1,  Rui-Huan Liu 1,  Ming-Hua Yang 1,  Ling-Yi Kong 1
Affiliations

Affiliation

  • 1 a State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
PMID: 26923350 DOI: 10.1080/14786419.2016.1146888
Abstract

One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known Alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginosa with an MIC value of 7.13 μg/ml.

Keywords

Evodia rutaecarpa; Rutaceae; antibacterial activity; indole alkaloids; quinolone alkaloids.

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