2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. KT2-962

KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC50=500 nM). KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases.

For research use only. We do not sell to patients.

KT2-962

KT2-962 Chemical Structure

CAS No. : 129648-96-0

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KT2-962 Related Antibodies

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DP EP FP IP TXA2/TP TXB2

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Description

KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC50=500 nM). KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases[1].

IC50 & Target

TXA2 Receptor

 

Molecular Weight

518.02

Formula

C23H25ClNNaO5S2
CAS No.
SMILES

O=S(C1=C2C=CC(C(C)C)=CC=C2C(CCCCNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)(O[Na])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KT2-962 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KT2-962129648-96-0Prostaglandin ReceptorTXA2hydroxyl radicalvascular diseasesInhibitorinhibitorinhibit

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HY-19129
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