2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. iAfaPhos1

iAfaPhos1 is a FKBP12F36V epimer ligand. iAfaPhos1 leads to reduced dephosphorylation of EGFR at pY1068 and pY845 sites. iAfaPhos1 has anticancer activity against non-small cell lung cancer.

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iAfaPhos1

iAfaPhos1 Chemical Structure

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Other Forms of iAfaPhos1:

iAfaPhos1 Related Antibodies

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Description

iAfaPhos1 is a FKBP12F36V epimer ligand. iAfaPhos1 leads to reduced dephosphorylation of EGFR at pY1068 and pY845 sites. iAfaPhos1 has anticancer activity against non-small cell lung cancer[1].

Molecular Weight

1222.79

Formula

C64H77ClFN7O14
SMILES

O=C(COC1=CC([C@@H](CCC2=CC=C(C(OC)=C2)OC)OC([C@H]3CCCCN3C([C@H](C4=CC(OC)=C(C(OC)=C4)OC)CC)=O)=O)=CC=C1)NCCOCCOCCN(C/C=C/C(NC5=CC6=C(C=C5OC)N=CN=C6NC7=CC=C(C(Cl)=C7)F)=O)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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iAfaPhos1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

iAfaPhos1iAfaPhos 1iAfaPhos-1EGFREpidermal growth factor receptorErbB-1HER1H1975 cellsHeLa cellsInhibitorinhibitorinhibit

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