2. Metabolic Enzyme/Protease
  3. Angiotensin-converting Enzyme (ACE)
  4. HOE-288

HOE-288 is an orally active angiotensin-converting enzyme (ACE) inhibitor. HOE-288 can be used for the research of neurological disease.

For research use only. We do not sell to patients.

HOE-288

HOE-288 Chemical Structure

CAS No. : 93231-79-9

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Description

HOE-288 is an orally active angiotensin-converting enzyme (ACE) inhibitor. HOE-288 can be used for the research of neurological disease[1].

In Vivo

HOE-288 (10 nmol I.C.V.) attenuates the Scopolamine (HY-N0296)-induced memory deficit in rats[1].
HOE-288 (10 mg/kg, i.g., daily for 1 weeks) results in a marked inhibition of CE activity in the brain cortex, the hypothalamus, and in the brainstem in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

470.60

Formula

C27H38N2O5
CAS No.
SMILES

O=C(C1N(CC2(CC3CCC2CC3)C1)C(C(C)NC(CCC4=CC=CC=C4)C(OCC)=O)=O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HOE-288 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HOE-28893231-79-9HOE288HOE 288Angiotensin-converting Enzyme (ACE)angiotensin-converting enzymeACEneurologicalInhibitorinhibitorinhibit

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