2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. GYKI 12743

GYKI 12743 is a vasoselective, postsynaptic α-adrenoceptor blocker. GYKI 12743 inhibits but does not completely eliminate the cutaneous microcirculatory blood flow reduction evoked by electrical stimulation of the peripheral stump of the cut saphenous nerve in rats. GYKI 12743 can be used for the study of neurological diseases.

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GYKI 12743

GYKI 12743 Chemical Structure

CAS No. : 110714-10-8

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Description

GYKI 12743 is a vasoselective, postsynaptic α-adrenoceptor blocker. GYKI 12743 inhibits but does not completely eliminate the cutaneous microcirculatory blood flow reduction evoked by electrical stimulation of the peripheral stump of the cut saphenous nerve in rats. GYKI 12743 can be used for the study of neurological diseases[1].

Molecular Weight

337.80

Formula

C16H20ClN3O3
CAS No.
SMILES

O=C(C=CC=N1)N1CCCNCC2OC3=C(C=CC=C3)OC2.Cl
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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GYKI 12743 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GYKI 12743110714-10-8GYKI12743GYKI-12743Adrenergic ReceptorBeta Receptorneurological diseases,α-adrenoceptorInhibitorinhibitorinhibit

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