2. GPCR/G Protein
  3. Guanylate Cyclase
  4. GSK2181236A

GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension.

For research use only. We do not sell to patients.

GSK2181236A

GSK2181236A Chemical Structure

CAS No. : 1160426-89-0

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GSK2181236A Related Antibodies

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Description

GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension[1].

Molecular Weight

613.51

Formula

C31H21F6N3O4
CAS No.
SMILES

O=C(C1=C(C(F)(F)F)N(C2=NC(C3=CC=CC=C3OCC4=CC=C(C5=CC=C(OC(F)(F)F)C=C5)C=C4C)=CC=C2)N=C1)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK2181236A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK2181236A1160426-89-0Guanylate CyclaseNOsoluble guanylate cyclasesGCcardiac hypertrophyhypertensionInhibitorinhibitorinhibit

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