2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. GR 250495X

GR 250495X is an inhaled glucocorticoid receptor agonist. GR 250495X is designed as a antedrug, which takes effect locally in the lungs but is rapidly metabolized and inactivated in the bloodstream after entering the systemic circulation, thereby minimizing systemic side effects. GR 250495X can be used in asthma research.

For research use only. We do not sell to patients.

GR 250495X

GR 250495X Chemical Structure

CAS No. : 192057-17-3

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Description

GR 250495X is an inhaled glucocorticoid receptor agonist. GR 250495X is designed as a antedrug, which takes effect locally in the lungs but is rapidly metabolized and inactivated in the bloodstream after entering the systemic circulation, thereby minimizing systemic side effects. GR 250495X can be used in asthma research[1].

Molecular Weight

554.64

Formula

C28H36F2O7S
CAS No.
SMILES

O=C(OCC1)[C@H]1SC([C@]23[C@@]4([C@@]([C@@]5([H])[C@]([C@H](C4)O)([C@@]6(C([C@H](C5)F)=CC(CC6)=O)C)F)([H])C[C@@]2([H])O[C@H](O3)CCC)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GR 250495X Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR 250495X192057-17-3Glucocorticoid Receptorclinical potentialasthmaInhibitorinhibitorinhibit

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