2. Neuronal Signaling
  3. Amyloid-β
  4. GLY-230

GLY-230 is an orally active compound. GLY-230 can inhibit nonenzymatic glycation and reduce glycated albumin. GLY-230 can reduce brain Aβ42 levels. GLY-230 can be used for the researches of metabolic and neurological disease, such as diabetic renal dysfunction.

For research use only. We do not sell to patients.

GLY-230

GLY-230 Chemical Structure

CAS No. : 320777-05-7

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Description

GLY-230 is an orally active compound. GLY-230 can inhibit nonenzymatic glycation and reduce glycated albumin. GLY-230 can reduce brain Aβ42 levels. GLY-230 can be used for the researches of metabolic and neurological disease, such as diabetic renal dysfunction[1][2].

In Vivo

GLY-230 (7.5 mg/kg, p.o., twice a day for 14 days) reduces brain Aβ42 and increased plasma Aβ42 levels in transgenic mice expressing APP[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

261.70

Formula

C14H12ClNO2
CAS No.
SMILES

OC(CC(C=CC=C1)=C1NC2=CC(Cl)=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GLY-230 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLY-230320777-05-7GLY230GLY 230Amyloid-ββ-amyloid peptideAβAbetanonenzymatic glycationglycated albuminAβ42metabolicneurologicaldiabetic renal dysfunctiondiabete,Inhibitorinhibitorinhibit

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