2. Gene
  3. Chi3l1 - chitinase 3 like 1 Gene

Chi3l1 - chitinase 3 like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Chil1; GP-39; CGP-39

Gene ID: 89824 | Gene type: protein coding

About Chi3l1

Summary

Predicted to enable chitin binding activity. Involved in cellular response to interleukin-1; cellular response to tumor necrosis factor; and inflammatory response. Located in extracellular space. Biomarker of hypertension. Human ortholog(s) of this gene implicated in asthma and schizophrenia. Orthologous to human CHI3L1 (chitinase 3 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Chi3l1 Products(2)

mRNA Protein Name
NM_001309820.1 NP_001296749.1 chitinase-3-like protein 1 isoform 1 precursor
NM_053560.2 NP_446012.2 chitinase-3-like protein 1 isoform 2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
16234240 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
16234240 RGD
involved in inflammatory response IEP
IEP: Inferred from expression pattern
16234240 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
16234240 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chitinase-3-like protein 1

cartilage glycoprotein 39

chitinase 3-like 1 (cartilage glycoprotein-39)

chitinase 3-like 1 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15275 BMS-265246 Inhibitor 99.59% Unkown
HY-148013 K284-6111 Inhibitor 99.94% Unkown
HY-163387 CHI3L1-IN-1 Inhibitor 99.68% Unkown
HY-163388 CHI3L1-IN-2 Inhibitor 98.19% Unkown
HY-RS02626 CHI3L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-171656 G721-0282 / Unkown
HY-175207 CHI3L1-IN-3 Inhibitor / Unkown
HY-RS16736 Chi3l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23173 Chi3l1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990366 Anti-CHI3L1 Antibody Inhibitor 99.49% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chi3l1 NCBI NCBI:1116
Mus musculus Chi3l1 NCBI