2. Gene
  3. Ucn3 - urocortin 3 Gene

Ucn3 - urocortin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ucn III

Gene ID: 83428 | Gene type: protein coding

About Ucn3

Summary

This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. The pancreatic islets isolated from mice lacking the encoded protein secrete less Insulin in response to high glucose concentrations. Transgenic mice overexpressing the encoded protein exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high-fat diet. [provided by RefSeq, Sep 2016]

Ucn3 Products(1)

mRNA Protein Name
NM_031250.5 NP_112540.2 urocortin-3 preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11416224 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11416224 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urocortin-3

Urocortin III

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1858A Urocortin III, mouse TFA Activator 95.07% Unkown
HY-P1858 Urocortin III, mouse Activator / Unkown
HY-RS15409 UCN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21451 Ucn3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ucn3 NCBI NCBI:114131