2. Gene
  3. Pros1 - protein S Gene

Pros1 - protein S Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pros

Gene ID: 81750 | Gene type: protein coding

About Pros1

Summary

Predicted to enable calcium ion binding activity. Involved in several processes, including liver development; positive regulation of phagocytosis; and response to lipopolysaccharide. Located in extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in autosomal dominant thrombophilia due to protein S deficiency; autosomal recessive thrombophilia due to protein S deficiency; cerebral infarction; and protein S deficiency. Orthologous to human PROS1 (protein S). [provided by Alliance of Genome Resources, Apr 2022]

Pros1 Products(1)

mRNA Protein Name
NM_031086.2 NP_112348.2 vitamin K-dependent protein S precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
7608128 RGD
Biological Process GO Annotation Evidence Reference Source
involved in liver development IEP
IEP: Inferred from expression pattern
7660357 RGD
involved in negative regulation of coagulation IDA
IDA: Inferred from direct assay
7608128 RGD
involved in positive regulation of phagocytosis IDA
IDA: Inferred from direct assay
15949798 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
20187850 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
16879219 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
16995903 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
7608128 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vitamin K-dependent protein S

protein S (alpha)

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0917 TO-PRO 1 ≥96.0% Unkown
HY-136298A X77 Inhibitor 99.95% Unkown
HY-110084 BTZO-1 99.32% Unkown
HY-P4388 Z-Arg-Leu-Arg-Gly-Gly-AMC 99.93% Unkown
HY-P4388A Z-Arg-Leu-Arg-Gly-Gly-AMC acetate 98.85% Unkown
HY-136298 (Rac)-X77 Inhibitor 99.65% Unkown
HY-D0918 YO-PRO-1 98.20% Unkown
HY-RS11202 PROS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-149655 D1N8 Inhibitor / Unkown
HY-154976 SARS-CoV-2-IN-50 Inhibitor / Unkown
HY-174352 TERT ligand-1 Inhibitor / Unkown
HY-157145 SARS-CoV-2-IN-69 Inhibitor / Unkown
HY-RS18835 Pros1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25327 Pros1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pros1 NCBI NCBI:5627