2. Gene
  3. Hnmt - histamine N-methyltransferase Gene

Hnmt - histamine N-methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81676 | Gene type: protein coding

About Hnmt

Summary

Enables histamine N-methyltransferase activity. Involved in several processes, including hyperosmotic response; response to cocaine; and response to interleukin-1. Located in neuron projection. Used to study brain infarction. Human ortholog(s) of this gene implicated in Parkinson's disease; asthma; atopic dermatitis; autosomal recessive non-syndromic intellectual disability; and essential tremor. Orthologous to human HNMT (histamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Hnmt Products(1)

mRNA Protein Name
NM_031044.3 NP_112306.1 histamine N-methyltransferase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables histamine N-methyltransferase activity IDA
IDA: Inferred from direct assay
1639806 RGD
Biological Process GO Annotation Evidence Reference Source
involved in S-adenosylmethionine metabolic process IDA
IDA: Inferred from direct assay
15739896 RGD
involved in histamine metabolic process IDA
IDA: Inferred from direct assay
15739896 RGD
involved in hyperosmotic response IEP
IEP: Inferred from expression pattern
2429527 RGD
involved in response to amine IEP
IEP: Inferred from expression pattern
3952132 RGD
involved in response to cocaine IEP
IEP: Inferred from expression pattern
9231750 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
2717067 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
10203252 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
8594930 RGD
involved in response to tumor cell IEP
IEP: Inferred from expression pattern
3111198 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histamine N-methyltransferase

HMT

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103056 DDD85646 99.72% Unkown
HY-153021 NMT-IN-1 Inhibitor ≥98.0% Unkown
HY-RS06259 HNMT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18765 Hnmt Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25252 Hnmt Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hnmt NCBI NCBI:3176