2. Gene
  3. Cblc - Casitas B-lineage lymphoma c Gene

Cblc - Casitas B-lineage lymphoma c Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cbl3; 2310076I21Rik; 2310079L19Rik

Gene ID: 80794 | Gene type: protein coding

About Cblc

Summary

Predicted to enable several functions, including SH3 domain binding activity; phosphotyrosine residue binding activity; and signaling receptor binding activity. Predicted to be involved in cellular protein metabolic process; negative regulation of protein kinase activity; and signal transduction. Predicted to be part of ubiquitin Ligase complex. Predicted to be active in membrane raft and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; lung; and sensory organ. Orthologous to human CBLC (Cbl proto-oncogene C). [provided by Alliance of Genome Resources, Apr 2022]

Cblc Products(2)

mRNA Protein Name
NM_001161844.1 NP_001155316.1 E3 ubiquitin-protein ligase CBL-C isoform 2
NM_023224.5 NP_075713.3 E3 ubiquitin-protein ligase CBL-C isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18753381 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
18753381 MGI
acts upstream of or within protein catabolic process IDA
IDA: Inferred from direct assay
18753381 MGI
acts upstream of or within protein stabilization IDA
IDA: Inferred from direct assay
18753381 MGI
acts upstream of or within response to glial cell derived neurotrophic factor IDA
IDA: Inferred from direct assay
18753381 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase CBL-C

CBL-3

RING-type E3 ubiquitin transferase CBL-C

SH3-binding protein CBL-3

SH3-binding protein CBL-C

signal transduction protein CBL-C

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B2209 Hydroxocobalamin 99.32% Yes
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107643 Reversan Inhibitor 99.57% Unkown
HY-154992 2,4-Difluorophenylethynylcobalamin 99.73% Unkown
HY-RS01998 CBLC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08509 MMACHC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19579 Cblc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26076 Cblc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cblc NCBI NCBI:23624