2. Gene
  3. Bhlhe40 - basic helix-loop-helix family, member e40 Gene

Bhlhe40 - basic helix-loop-helix family, member e40 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dec1; Bhlhb2; Sharp2; Stra13; Stra14; SHARP-2

Gene ID: 79431 | Gene type: protein coding

About Bhlhe40

Summary

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with Arntl or compete for E-box binding sites in the promoter of Per1 and repress Clock/Arntl's transactivation of Per1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]

Bhlhe40 Products(1)

mRNA Protein Name
NM_053328.2 NP_445780.2 class E basic helix-loop-helix protein 40
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
12397359 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
12954728 RGD
involved in regulation of neuronal synaptic plasticity IEP
IEP: Inferred from expression pattern
9532582 RGD
involved in response to light stimulus IDA
IDA: Inferred from direct assay
12397359 RGD
involved in response to light stimulus IEP
IEP: Inferred from expression pattern
12397359 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

class E basic helix-loop-helix protein 40

basic helix-loop-helix domain containing, class B2

class B basic helix-loop-helix protein 2

enhancer-of-split and hairy-related protein 2

stimulated by retinoic acid 14

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01493 BHLHE40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18433 Bhlhe40 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24914 Bhlhe40 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bhlhe40 NCBI NCBI:8553