2. Gene
  3. Fgr - FGR proto-oncogene, Src family tyrosine kinase Gene

Fgr - FGR proto-oncogene, Src family tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as p55-Fgr

Gene ID: 79113 | Gene type: protein coding

About Fgr

Summary

Enables protein tyrosine kinase activity. Predicted to be involved in several processes, including defense response to Other organism; protein phosphorylation; and regulation of kinase activity. Predicted to act upstream of or within bone mineralization and skeletal system morphogenesis. Located in cytosol and plasma membrane. Orthologous to human FGR (FGR proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Fgr Products(1)

mRNA Protein Name
NM_024145.3 NP_077059.2 tyrosine-protein kinase Fgr
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
7744027 RGD
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
15282299 RGD
Biological Process GO Annotation Evidence Reference Source
involved in myoblast proliferation IEP
IEP: Inferred from expression pattern
2425941 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase Fgr

Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog

Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

feline Gardner-Rasheed sarcoma viral oncogene

proto-oncogene c-Fgr

proto-oncogene tyrosine-protein kinase Fgr

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10230 Midostaurin 99.91% Yes
Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-10234 Saracatinib 99.92% Phase 3
HY-10234A Saracatinib difumarate Inhibitor 99.24% Phase 3
HY-15322 PRT062607 Inhibitor 99.38% Phase 2
HY-10186 TG 100801 Inhibitor 98.61% Phase 2
HY-10187 TG 100801 Hydrochloride Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15141 Staurosporine 99.98% Unkown
HY-112852 TL02-59 99.84% Unkown
HY-10185 TG 100572 Hydrochloride Inhibitor 98.76% Unkown
HY-10230S Midostaurin-d5 Inhibitor ≥98.0% Unkown
HY-10184 TG 100572 Inhibitor / Unkown
HY-112852A TL02-59 dihydrochloride / Unkown
HY-145373 BMS-986143 Inhibitor / Unkown
HY-RS04929 FGR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W751179 Midostaurin-13C6 / Unkown
HY-RS19562 Fgr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26058 Fgr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgr NCBI NCBI:2268
Mus musculus Fgr NCBI NCBI:14191