2. Gene
  3. Mcam - melanoma cell adhesion molecule Gene

Mcam - melanoma cell adhesion molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CD146; Muc18

Gene ID: 78967 | Gene type: protein coding

About Mcam

Summary

Involved in positive regulation of cell migration. Located in extracellular space and nucleus. Biomarker of impotence and malignant mesothelioma. Orthologous to human MCAM (melanoma cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Mcam Products(2)

mRNA Protein Name
NM_001034009.1 NP_001029181.1 cell surface glycoprotein MUC18 isoform 2 precursor
NM_023983.3 NP_076473.2 cell surface glycoprotein MUC18 isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cell migration IDA
IDA: Inferred from direct assay
21042736 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
23649916 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell surface glycoprotein MUC18

gicerin

l-gicerin

melanoma-associated antigen MUC18

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08215 MCAM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17964 Mcam Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24435 Mcam Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991609 ABX-MA1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcam NCBI NCBI:4162
Macaca fascicularis Mcam NCBI NCBI:101925966
Mus musculus Mcam NCBI NCBI:84004