2. Gene
  3. Kansl1 - KAT8 regulatory NSL complex subunit 1 Gene

Kansl1 - KAT8 regulatory NSL complex subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1267; 1700081L11Rik; 9430041J06Rik

Gene ID: 76719 | Gene type: protein coding

About Kansl1

Summary

Predicted to enable Histone Acetyltransferase binding activity. Predicted to be involved in histone H4-K16 acetylation; histone H4-K5 acetylation; and histone H4-K8 acetylation. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleoplasm. Predicted to be part of MLL1 complex and NSL complex. Is expressed in brain. Human ortholog(s) of this gene implicated in Koolen de Vries syndrome. Orthologous to human KANSL1 (KAT8 regulatory NSL complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Kansl1 Products(5)

mRNA Protein Name
NM_001081045.2 NP_001074514.1 KAT8 regulatory NSL complex subunit 1 isoform 1
NM_001359634.1 NP_001346563.1 KAT8 regulatory NSL complex subunit 1 isoform 1
NM_001372458.1 NP_001359387.1 KAT8 regulatory NSL complex subunit 1 isoform 2
NM_001372459.1 NP_001359388.1 KAT8 regulatory NSL complex subunit 1 isoform 3
NM_001372460.1 NP_001359389.1 KAT8 regulatory NSL complex subunit 1 isoform 4
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
part of NSL complex IDA
IDA: Inferred from direct assay
24842875 MGI
is active in mitochondrion IDA
IDA: Inferred from direct assay
37813994 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

KAT8 regulatory NSL complex subunit 1

NSL complex protein NSL1

non-specific lethal 1 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07067 KANSL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20558 Kansl1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27067 Kansl1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kansl1 NCBI NCBI:284058